1-(5'-O-trityl-2',3'-di-O-acetyl-β-D-ribofuranosyl)-6-nitroindole

Base Information

• Chemical Name: 1-(5'-O-trityl-2',3'-di-O-acetyl-β-D-ribofuranosyl)-6-nitroindole
• CAS No.: 62515-56-4
• Molecular Formula: C₃₆H₃₂N₂O₈
• Molecular Weight: 620.659
• Mol file: 62515-56-4.mol

Synonyms:1-(5'-O-trityl-2',3'-di-O-acetyl-β-D-ribofuranosyl)-6-nitroindole

Chemical Property of 1-(5'-O-trityl-2',3'-di-O-acetyl-β-D-ribofuranosyl)-6-nitroindole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(5'-O-trityl-2',3'-di-O-acetyl-β-D-ribofuranosyl)-6-nitroindole

There total 5 articles about 1-(5'-O-trityl-2',3'-di-O-acetyl-β-D-ribofuranosyl)-6-nitroindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

1-(5'-O-trityl-2',3'-di-O-acetyl-β-D-ribofuranosyl)-6-nitroindoline (131508-35-5) → 1-(5'-O-trityl-2',3'-di-O-acetyl-β-D-ribofuranosyl)-6-nitroindole (62515-56-4)

Guidance literature:

With manganese(IV) oxide; In benzene; for 4h; Heating;

DOI:10.1007/BF00476979

Reference yield:

6-nitroindoline (19727-83-4) → 1-(5'-O-trityl-2',3'-di-O-acetyl-β-D-ribofuranosyl)-6-nitroindole (62515-56-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 95 percent / ethanol; benzene / 5 h / Heating

2: 100 percent / pyridine / 18 h

3: 70 percent / MnO₂ (activated) / benzene / 4 h / Heating

With pyridine; manganese(IV) oxide; In ethanol; benzene;

DOI:10.1007/BF00476979

Reference yield:

(3R,4S,5R)-5-((trityloxy)methyl)tetrahydrofuran-2,3,4-triol (55726-00-6,72521-12-1,72521-13-2,72521-20-1,72521-21-2,72521-22-3,131285-09-1,131285-24-0) → 1-(5'-O-trityl-2',3'-di-O-acetyl-β-D-ribofuranosyl)-6-nitroindole (62515-56-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 95 percent / ethanol; benzene / 5 h / Heating

2: 100 percent / pyridine / 18 h

3: 70 percent / MnO₂ (activated) / benzene / 4 h / Heating

With pyridine; manganese(IV) oxide; In ethanol; benzene;

DOI:10.1007/BF00476979

upstream raw materials:

1-(5'-O-trityl-2',3'-di-O-acetyl-β-D-ribofuranosyl)-6-nitroindoline

6-nitroindoline

(3R,4S,5R)-5-((trityloxy)methyl)tetrahydrofuran-2,3,4-triol

1-(5'-O-trityl-β-ribofuranosyl)-6-nitroindoline

Downstream raw materials:

1-(β-D-ribopyranosyl)-6-nitroindole