Technology Process of 4′,5′-dibromo-2′-hydroxyacetophenone
There total 4 articles about 4′,5′-dibromo-2′-hydroxyacetophenone which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
4'-bromo-2'-hydroxyacetophenone;
With
zinc(II) chloride;
In
carbon disulfide;
at 0 ℃;
for 0.25h;
Inert atmosphere;
With
bromine;
In
carbon disulfide;
at 0 - 20 ℃;
Solvent;
Reagent/catalyst;
Catalytic behavior;
Inert atmosphere;
DOI:10.1055/s-0036-1588376
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium acetate / 2.5 h / Inert atmosphere; Reflux
2.1: aluminum (III) chloride / 3 h / 170 °C / Inert atmosphere
3.1: zinc(II) chloride / carbon disulfide / 0.25 h / 0 °C / Inert atmosphere
3.2: 0 - 20 °C / Inert atmosphere
With
aluminum (III) chloride; sodium acetate; zinc(II) chloride;
In
carbon disulfide;
2.1: |Fries Phenol Ester Rearrangement;
DOI:10.1055/s-0036-1588376
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: aluminum (III) chloride / 3 h / 170 °C / Inert atmosphere
2.1: zinc(II) chloride / carbon disulfide / 0.25 h / 0 °C / Inert atmosphere
2.2: 0 - 20 °C / Inert atmosphere
With
aluminum (III) chloride; zinc(II) chloride;
In
carbon disulfide;
1.1: |Fries Phenol Ester Rearrangement;
DOI:10.1055/s-0036-1588376
