methyl 1-O-(4-ethoxycarbonylphenyl)-2,3,4-tri-O-acetyl-β-D-glucopyranosiduronate

Base Information

• Chemical Name: methyl 1-O-(4-ethoxycarbonylphenyl)-2,3,4-tri-O-acetyl-β-D-glucopyranosiduronate
• CAS No.: 1376574-24-1
• Molecular Formula: C₂₂H₂₆O₁₂
• Molecular Weight: 482.441
• Mol file: 1376574-24-1.mol

Synonyms:methyl 1-O-(4-ethoxycarbonylphenyl)-2,3,4-tri-O-acetyl-β-D-glucopyranosiduronate

Chemical Property of methyl 1-O-(4-ethoxycarbonylphenyl)-2,3,4-tri-O-acetyl-β-D-glucopyranosiduronate

Chemical Property:

Purity/Quality:

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Technology Process of methyl 1-O-(4-ethoxycarbonylphenyl)-2,3,4-tri-O-acetyl-β-D-glucopyranosiduronate

There total 1 articles about methyl 1-O-(4-ethoxycarbonylphenyl)-2,3,4-tri-O-acetyl-β-D-glucopyranosiduronate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

Ethyl 4-hydroxybenzoate (120-47-8) + methyl 2,3,4-tri-O-acetyl-1-O-(trichloroacetimidoyl)-α-D-glucopyranuronate (92420-89-8) → methyl 1-O-(4-ethoxycarbonylphenyl)-2,3,4-tri-O-acetyl-β-D-glucopyranosiduronate (1376574-24-1)

Guidance literature:

With boron trifluoride diethyl etherate; In dichloromethane; at -20 - 15 ℃; for 4h; Inert atmosphere; Molecular sieve;

DOI:10.1016/j.tet.2012.03.100

Reference yield: 51.0%

methyl 1-O-(4-ethoxycarbonylphenyl)-2,3,4-tri-O-acetyl-β-D-glucopyranosiduronate (1376574-24-1) → 4-carboxyphenyl-β-D-glucopyranosiduronic acid dipotassium salt

Guidance literature:

With water; potassium hydroxide; In methanol; at 0 - 4 ℃; for 72h; Inert atmosphere;

DOI:10.1016/j.tet.2012.03.100

upstream raw materials:

Ethyl 4-hydroxybenzoate

methyl 2,3,4-tri-O-acetyl-1-O-(trichloroacetimidoyl)-α-D-glucopyranuronate