Tert-butyl 4-amino-2-chlorobenzoate

Base Information

Chemical Name:Tert-butyl 4-amino-2-chlorobenzoate
CAS No.:75294-49-4
Molecular Formula:C11H14 Cl N O2
Molecular Weight:227.691
Hs Code.:
European Community (EC) Number:831-938-6
DSSTox Substance ID:DTXSID90700582
Wikidata:Q82632001
Mol file:75294-49-4.mol

Synonyms:TERT-BUTYL 4-AMINO-2-CHLOROBENZOATE;75294-49-4;tert-Butyl4-amino-2-chlorobenzoate;SCHEMBL355647;DTXSID90700582;LLOXEUOQRNPJJK-UHFFFAOYSA-N;MFCD08703413;AKOS010564148;SY262733;EN300-840521;Z802847758

Suppliers and Price of Tert-butyl 4-amino-2-chlorobenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
TERT-BUTYL-4-AMINO-2-CHLOROBENZOATE 95.00%
5MG
$ 498.42

AK Scientific
Tert-butyl4-amino-2-chlorobenzoate
100mg
$ 240.00

AK Scientific
Tert-butyl4-amino-2-chlorobenzoate
2.5g
$ 1116.00

Abosyn
tert-butyl4-amino-2-chlorobenzoate 95%-98%
1g
$ 562.00

Total 4 raw suppliers

Chemical Property of Tert-butyl 4-amino-2-chlorobenzoate

Chemical Property:

PSA：52.32000
LogP:3.45870
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:227.0713064
Heavy Atom Count:15
Complexity:237

Purity/Quality:

97% ^*data from raw suppliers

TERT-BUTYL-4-AMINO-2-CHLOROBENZOATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)C1=C(C=C(C=C1)N)Cl

Technology Process of Tert-butyl 4-amino-2-chlorobenzoate

There total 3 articles about Tert-butyl 4-amino-2-chlorobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 250790-05-7
tert-butyl 2-chloro-4-nitro-benzoate

: 75294-49-4
tert-butyl 4-amino-2-chlorobenzoate

Guidance literature:: With hydrogen; platinum on carbon; In ethanol; ethyl acetate; at 20 ℃; under 750.075 Torr;

Reference yield:

: 99-60-5
2-chloro-4-nitrobenzoic acid

: 75294-49-4
tert-butyl 4-amino-2-chlorobenzoate

Guidance literature:: Multi-step reaction with 2 steps

1: dmap; triethylamine / tetrahydrofuran / 14 h / -10 - 25 °C

2: ammonia hydrochloride; iron⁽⁰⁾ / ethanol; water monomer / 14 h / 25 °C

With dmap; iron⁽⁰⁾; ammonia hydrochloride; triethylamine; In tetrahydrofuran; ethanol; water monomer;