1-<2-(t-butyldiphenylsilyloxymethyl)phenyl>-1,1-diphenylmethanol

Base Information

• Chemical Name: 1-<2-(t-butyldiphenylsilyloxymethyl)phenyl>-1,1-diphenylmethanol
• CAS No.: 160375-88-2
• Molecular Formula: C₃₆H₃₆O₂Si
• Molecular Weight: 528.766
• Mol file: 160375-88-2.mol

Synonyms:1-<2-(t-butyldiphenylsilyloxymethyl)phenyl>-1,1-diphenylmethanol

Chemical Property of 1-<2-(t-butyldiphenylsilyloxymethyl)phenyl>-1,1-diphenylmethanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-<2-(t-butyldiphenylsilyloxymethyl)phenyl>-1,1-diphenylmethanol

There total 1 articles about 1-<2-(t-butyldiphenylsilyloxymethyl)phenyl>-1,1-diphenylmethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

α,α-Diphenyl-1,2-benzoldimethanol (21464-41-5) + tert-butylchlorodiphenylsilane (58479-61-1) → 1-<2-(t-butyldiphenylsilyloxymethyl)phenyl>-1,1-diphenylmethanol (160375-88-2)

Guidance literature:

With 1H-imidazole; In tetrahydrofuran; for 16h; Ambient temperature;

DOI:10.1080/15257779408011868

Reference yield:

1-<2-(t-butyldiphenylsilyloxymethyl)phenyl>-1,1-diphenylmethanol (160375-88-2) → 1-<2-(t-butyldiphenylsilyloxymethyl)phenyl>-1,1-diphenylmethyl chloride (160375-72-4)

Guidance literature:

With acetyl chloride; In toluene; for 46h; Yield given; Heating;

DOI:10.1080/15257779408011868

Reference yield:

1-<2-(t-butyldiphenylsilyloxymethyl)phenyl>-1,1-diphenylmethanol (160375-88-2) → N6-cyclohexyl-5'-O-<(2-t-butyldiphenylsilyloxymethylphenyl)diphenylmethyl>adenosine (160375-76-8)

Guidance literature:

Multi-step reaction with 2 steps

1: acetyl chloride / toluene / 46 h / Heating

2: 30 percent / CH₂Cl₂; pyridine / 18 h / Ambient temperature

With acetyl chloride; In pyridine; dichloromethane; toluene;

DOI:10.1080/15257779408011868

upstream raw materials:

α,α-Diphenyl-1,2-benzoldimethanol

tert-butylchlorodiphenylsilane

Downstream raw materials:

1-<2-(t-butyldiphenylsilyloxymethyl)phenyl>-1,1-diphenylmethyl chloride

N⁶-cyclohexyl-5'-O-<(2-t-butyldiphenylsilyloxymethylphenyl)diphenylmethyl>adenosine