5-(3,4-Dichlorophenyl)imidazolidine-2,4-dione

Base Information

Chemical Name:5-(3,4-Dichlorophenyl)imidazolidine-2,4-dione
CAS No.:74311-02-7
Molecular Formula:C₁₀H₁₀N₂O₂
Molecular Weight:190.202
Hs Code.:
NSC Number:64200,28555
DSSTox Substance ID:DTXSID30995834
ChEMBL ID:CHEMBL3245199

Synonyms:5-(3,4-dichlorophenyl)imidazolidine-2,4-dione;74311-02-7;7153-28-8;5-(3,4-Dichlorophenyl)hydantoin;NSC28555;Hydantoin, 5-(3,4-dichlorophenyl)-;SCHEMBL5580256;CHEMBL3245199;DTXSID30995834;UZHGPHDIPRADRK-UHFFFAOYSA-N;NSC64200;BHS100057;NSC 28555;NSC 64200;NSC-28555;NSC-64200;AKOS009075602;4-(3,4-Dichlorophenyl)-4H-imidazole-2,5-diol;5-(3,4-dichlorophenyl)-imidazolidine-2,4-dione

Suppliers and Price of 5-(3,4-Dichlorophenyl)imidazolidine-2,4-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 5-(3,4-Dichlorophenyl)imidazolidine-2,4-dione

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:243.9806328
Heavy Atom Count:15
Complexity:298

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=C(C=C1C2C(=O)NC(=O)N2)Cl)Cl

Technology Process of 5-(3,4-Dichlorophenyl)imidazolidine-2,4-dione

There total 8 articles about 5-(3,4-Dichlorophenyl)imidazolidine-2,4-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 673-06-3,25191-15-5,658-69-5,67675-33-6
D-(R)-phenylalanine

: 917-61-3
sodium isocyanate

: 74311-02-7
(5R)-(phenylmethyl)-2,4-imidazolidinedione

Guidance literature:: D-(R)-phenylalanine; sodium isocyanate; In water; at 50 ℃; for 0.5h;

With hydrogenchloride; In water; for 2h; Reflux;
DOI:10.1021/jm201243p

Reference yield:

: 3775-01-7,74805-60-0,109754-06-5
5-benzylidenehydantoin

: 74311-02-7
(5R)-(phenylmethyl)-2,4-imidazolidinedione

: 40857-14-5
(5S)-(phenylmethyl)-2,4-imidazolidinedione

Guidance literature:: With (R)-3,3'-bis(2,4,6-triisopropylphenyl)binol phosphoric acid; palladium(II) trifluoroacetate; hydrogen; (R)-2,2'-bis(diphenylphosphanyl)-1,1'-binaphthyl; In 2,2,2-trifluoroethanol; at 70 ℃; for 24h; under 30402 Torr; Reagent/catalyst; Temperature; Pressure; Overall yield = 95 %; enantioselective reaction; Catalytic behavior; Schlenk technique; Autoclave;
DOI:10.1016/j.tetasy.2016.10.006

Reference yield:

: 590-28-3
potassium cyanate

: 7524-50-7
methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

: 74311-02-7
(5R)-(phenylmethyl)-2,4-imidazolidinedione

: 40857-14-5
(5S)-(phenylmethyl)-2,4-imidazolidinedione

Guidance literature:: potassium cyanate; methyl (2S)-2-amino-3-phenylpropanoate hydrochloride; In water; at 20 ℃; Milling; Green chemistry;

With potassium carbonate; In water; at 20 ℃; Overall yield = 80 %; Overall yield = 173.9 mg; Green chemistry;
DOI:10.1021/jo5017629