Boc-Gly-Gln-Cys(MBzl)-Thr-Cys(MBzl)-Ser-Gly-Cys(MBzl)-Gly-Lys(Z)-OBzl

Base Information

• Chemical Name: Boc-Gly-Gln-Cys(MBzl)-Thr-Cys(MBzl)-Ser-Gly-Cys(MBzl)-Gly-Lys(Z)-OBzl
• CAS No.: 131453-28-6
• Molecular Formula: C₇₇H₁₀₂N₁₂O₂₁S₃
• Molecular Weight: 1627.92

Synonyms:Boc-Gly-Gln-Cys(MBzl)-Thr-Cys(MBzl)-Ser-Gly-Cys(MBzl)-Gly-Lys(Z)-OBzl

Chemical Property of Boc-Gly-Gln-Cys(MBzl)-Thr-Cys(MBzl)-Ser-Gly-Cys(MBzl)-Gly-Lys(Z)-OBzl

Chemical Property:

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Technology Process of Boc-Gly-Gln-Cys(MBzl)-Thr-Cys(MBzl)-Ser-Gly-Cys(MBzl)-Gly-Lys(Z)-OBzl

There total 1 articles about Boc-Gly-Gln-Cys(MBzl)-Thr-Cys(MBzl)-Ser-Gly-Cys(MBzl)-Gly-Lys(Z)-OBzl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.2%

(S)-2-{2-[(R)-2-(2-{(S)-2-[(R)-2-Amino-3-(4-methoxy-benzylsulfanyl)-propionylamino]-3-hydroxy-propionylamino}-acetylamino)-3-(4-methoxy-benzylsulfanyl)-propionylamino]-acetylamino}-6-benzyloxycarbonylamino-hexanoic acid benzyl ester; compound with trifluoro-acetic acid (131453-27-5) + Boc-Gly-Gln-Cys(MBzl)-Thr-N3 (131453-26-4) → Boc-Gly-Gln-Cys(MBzl)-Thr-Cys(MBzl)-Ser-Gly-Cys(MBzl)-Gly-Lys(Z)-OBzl (131453-28-6)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; at 4 ℃; for 72h;

DOI:10.1248/cpb.38.2112

Reference yield:

Boc-Gly-Gln-Cys(MBzl)-Thr-Cys(MBzl)-Ser-Gly-Cys(MBzl)-Gly-Lys(Z)-OBzl (131453-28-6) → C72H94N12O19S3*C2HF3O2 (131453-30-0)

Guidance literature:

With methoxybenzene; trifluoroacetic acid;

DOI:10.1248/cpb.38.2112

upstream raw materials:

(S)-2-{2-[(R)-2-(2-{(S)-2-[(R)-2-Amino-3-(4-methoxy-benzylsulfanyl)-propionylamino]-3-hydroxy-propionylamino}-acetylamino)-3-(4-methoxy-benzylsulfanyl)-propionylamino]-acetylamino}-6-benzyloxycarbonylamino-hexanoic acid benzyl ester; compound with trifluoro-acetic acid

Boc-Gly-Gln-Cys(MBzl)-Thr-N₃

Downstream raw materials:

C₇₂H₉₄N₁₂O₁₉S₃*C₂HF₃O₂

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