1-(p-nitrobenzoyl)-5-(1-propoxy)-3-(2-phenylethyl)pyrazolidine

Base Information

• Chemical Name: 1-(p-nitrobenzoyl)-5-(1-propoxy)-3-(2-phenylethyl)pyrazolidine
• CAS No.: 771578-68-8
• Molecular Formula: C₂₁H₂₅N₃O₄
• Molecular Weight: 383.447
• Mol file: 771578-68-8.mol

Synonyms:1-(p-nitrobenzoyl)-5-(1-propoxy)-3-(2-phenylethyl)pyrazolidine

Chemical Property of 1-(p-nitrobenzoyl)-5-(1-propoxy)-3-(2-phenylethyl)pyrazolidine

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of 1-(p-nitrobenzoyl)-5-(1-propoxy)-3-(2-phenylethyl)pyrazolidine

There total 1 articles about 1-(p-nitrobenzoyl)-5-(1-propoxy)-3-(2-phenylethyl)pyrazolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

vinyl propyl ether (764-47-6) + (E)-4-nitro-N'-(3-phenylpropylidene)benzohydrazide → 1-(p-nitrobenzoyl)-5-(1-propoxy)-3-(2-phenylethyl)pyrazolidine + 1-(p-nitrobenzoyl)-5-(1-propoxy)-3-(2-phenylethyl)pyrazolidine (771578-68-8)

Guidance literature:

With zircornium(IV) n-propoxide; (R)-3,3'-diiodo-2,2'-dihydroxy-1,1'-binaphthyl; In toluene; at 0 ℃; for 18h; Title compound not separated from byproducts;

DOI:10.1021/ja049498l

Reference yield:

1-(p-nitrobenzoyl)-5-(1-propoxy)-3-(2-phenylethyl)pyrazolidine (771578-68-8) → 5-phenethyl-4,5-dihydro-1H-pyrazole

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at -78 ℃; for 9h;

DOI:10.1021/ja049498l

Reference yield:

1-ethylthio-1-(trimethylsiloxy)ethene (63584-41-8) + 1-(p-nitrobenzoyl)-5-(1-propoxy)-3-(2-phenylethyl)pyrazolidine (771578-68-8) → S-ethyl (5-(2-phenylethyl)-2-(p-nitrobenzoyl)pyrazolidin-3-yl)ethanethioate

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; In acetonitrile; at 0 ℃; for 24h;

DOI:10.1021/ja049498l

upstream raw materials:

vinyl propyl ether