(E)-3-(4-Methoxy-phenyl)-acrylic acid benzotriazol-1-yl ester

Base Information

• Chemical Name: (E)-3-(4-Methoxy-phenyl)-acrylic acid benzotriazol-1-yl ester
• CAS No.: 141381-74-0
• Molecular Formula: C₁₆H₁₃N₃O₃
• Molecular Weight: 295.298
• Mol file: 141381-74-0.mol

Synonyms:(E)-3-(4-Methoxy-phenyl)-acrylic acid benzotriazol-1-yl ester

Chemical Property of (E)-3-(4-Methoxy-phenyl)-acrylic acid benzotriazol-1-yl ester

Chemical Property:

Purity/Quality:

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Technology Process of (E)-3-(4-Methoxy-phenyl)-acrylic acid benzotriazol-1-yl ester

There total 1 articles about (E)-3-(4-Methoxy-phenyl)-acrylic acid benzotriazol-1-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

3-(4'-methoxyphenyl)propenoic acid (830-09-1) + 1H-benzo[d][1,2,3]triazol-1-yl 2-nitrobenzenesulfonate (141381-72-8) → (E)-3-(4-Methoxy-phenyl)-acrylic acid benzotriazol-1-yl ester (141381-74-0) + 2-Nitro-benzenesulfonic acid; compound with triethyl-amine

Guidance literature:

With triethylamine; In acetonitrile; Ambient temperature;

Reference yield: 76.0%

4-methyl-N-(1-phenylethylidene)benzenesulfonamide (24865-83-6) + (E)-3-(4-Methoxy-phenyl)-acrylic acid benzotriazol-1-yl ester (141381-74-0) → (S)-4-(4-methoxyphenyl)-6-phenyl-1-tosyl-3,4-dihydropyridin-2(1H)-one

Guidance literature:

With (5aR,10bS)-5a,10b-dihydro-2-(2,4,6-trimethylphenyl)-4H,6H-indeno[2,1-b]-1,2,4-triazolo[4,3-d]-1,4-oxazinium chloride; 1,8-diazabicyclo[5.4.0]undec-7-ene; In toluene; at 0 ℃; for 14h; enantioselective reaction; Inert atmosphere;

DOI:10.1002/adsc.201600136

upstream raw materials:

3-(4'-methoxyphenyl)propenoic acid

1H-benzo[d][1,2,3]triazol-1-yl 2-nitrobenzenesulfonate