1-BROMO-1,2,3,4-TETRAHYDRONAPHTHALENE

Base Information

• Chemical Name: 1-BROMO-1,2,3,4-TETRAHYDRONAPHTHALENE
• CAS No.: 75238-77-6
• Molecular Formula: C10H11 Br
• Molecular Weight: 211.101
• Mol file: 75238-77-6.mol

Synonyms:1,2,3,4-Tetrahydro-1-naphthylbromide; 1-Bromo-1,2,3,4-tetrahydronaphthalene; 1-Bromotetralin; a-Bromotetralin; a-Tetralyl bromide

Chemical Property of 1-BROMO-1,2,3,4-TETRAHYDRONAPHTHALENE

Chemical Property:

• PSA: 0.00000
• LogP: 3.45890

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-Bromo-1,2,3,4-tetrahydro-naphthalene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-BROMO-1,2,3,4-TETRAHYDRONAPHTHALENE

There total 5 articles about 1-BROMO-1,2,3,4-TETRAHYDRONAPHTHALENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1,2,3,4-Tetrahydro-1-naphthol (529-33-9) → 1-Bromo-1,2,3,4-tetrahydronaphthalene (75238-77-6)

Guidance literature:

With trimethylsilyl bromide; In neat (no solvent); at 20 ℃; for 3h; chemoselective reaction; Green chemistry;

DOI:10.1016/j.tetlet.2016.04.083

Reference yield: 5.7%

tetralin (119-64-2) → 1-Bromo-1,2,3,4-tetrahydronaphthalene (75238-77-6) + 2-bromo-1,2,3,4-tetrahydronaphthalene (54753-94-5)

Guidance literature:

With styrene-4-vinyl(N-alkylpyridinium bromide); In water; acetic acid; at 23 ℃; for 24h;

DOI:10.1016/S0040-4020(01)85800-2

Reference yield:

tetralin (119-64-2) → 1-Bromo-1,2,3,4-tetrahydronaphthalene (75238-77-6)

Guidance literature:

With bromine;

DOI:10.1135/cccc20001791

upstream raw materials:

1,2,3,4-Tetrahydro-1-naphthol

tetralin

1,2-Dihydronaphthalene

3,4-dihydronaphthalene-1(2H)-one

Downstream raw materials:

1,2,3,4-Tetrahydro-naphth-1-yl-hydrazin

trans-2-bromo-1,2,3,4-tetrahydronaphthalen-1-ol

1,2-Dihydronaphthalene

allyl 1-(1,2,3,4-tetrahydro)-naphtyl thioether

Refernces

• 1、 -. "ATF6 MODULATORS AND USES THEREOF". Paragraph 185; 186. . Retrieved 2021/04/17.
• 2、 Ajvazi, Njomza,Stavber, Stojan. "Direct halogenation of alcohols with halosilanes under catalyst- and organic solvent-free reaction conditions". supporting information. p. 2430 - 2433. Retrieved 2016/05/19.