3-tert-butyl-4-fluorotoluene

Base Information

• Chemical Name: 3-tert-butyl-4-fluorotoluene
• CAS No.: 262361-36-4
• Molecular Formula: C₁₁H₁₅F
• Molecular Weight: 166.239
• Mol file: 262361-36-4.mol

Synonyms:3-tert-butyl-4-fluorotoluene

Chemical Property of 3-tert-butyl-4-fluorotoluene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-tert-butyl-4-fluorotoluene

There total 2 articles about 3-tert-butyl-4-fluorotoluene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

p-fluorotoluene (352-32-9) + tertiary butyl chloride (507-20-0) → 3-tert-butyl-4-fluorotoluene (262361-36-4)

Guidance literature:

aluminium trichloride; In carbon disulfide;

Reference yield: 35.0%

p-fluorotoluene (352-32-9) + tertiary butyl chloride (507-20-0) → 3-tert-butyl-4-fluorotoluene (262361-36-4) + 1,3-di-tert-butyl-2-fluoro-5-methylbenzene (1610366-32-9)

Guidance literature:

With aluminum (III) chloride; at 0 - 20 ℃; for 12h; Inert atmosphere;

DOI:10.1021/np500260z

Reference yield: 83.0%

3-tert-butyl-4-fluorotoluene (262361-36-4) → 3-tert-butyl-4-fluorobenzyl bromide (262361-37-5)

Guidance literature:

With N-Bromosuccinimide; dibenzoyl peroxide; In tetrachloromethane; hexane; water;

upstream raw materials:

p-fluorotoluene

tertiary butyl chloride

Downstream raw materials:

3-tert-butyl-4-fluorobenzyl bromide

3-tert-butyl-4-fluorobenzyl iodide