(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoic acid (S)-(-)-α-methylbenzylamine salt

Base Information

Chemical Name:(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoic acid (S)-(-)-α-methylbenzylamine salt
CAS No.:862994-68-1
Molecular Formula:C₈H₁₁N*C₂₂H₂₈FN₃O₆S
Molecular Weight:602.727
Hs Code.:

(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoic acid (S)-(-)-α-methylbenzylamine salt

Synonyms:(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoic acid (S)-(-)-α-methylbenzylamine salt

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Chemical Property of (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoic acid (S)-(-)-α-methylbenzylamine salt

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Technology Process of (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoic acid (S)-(-)-α-methylbenzylamine salt

There total 1 articles about (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoic acid (S)-(-)-α-methylbenzylamine salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2627-86-3
(S)-1-phenyl-ethylamine

: 287714-41-4
rosuvastatin

: 862994-68-1
(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoic acid (S)-(-)-α-methylbenzylamine salt

Guidance literature:: In acetonitrile;

Reference yield:

: 862994-68-1
(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoic acid (S)-(-)-α-methylbenzylamine salt

: crestor

Guidance literature:: (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoic acid (S)-(-)-α-methylbenzylamine salt; With hydrogenchloride; In water; ethyl acetate; at 5 - 10 ℃; for 0.25h;

With sodium hydroxide; In tert-butyl methyl ether; water; at 15 - 20 ℃; for 0.333333h;

With calcium acetate; In tert-butyl methyl ether; water; at 20 - 25 ℃;