2-Amino-3-(4-trifluoromethylsulfanyl-phenyl)-propionic acid

Base Information

Chemical Name:2-Amino-3-(4-trifluoromethylsulfanyl-phenyl)-propionic acid
CAS No.:126300-91-2
Molecular Formula:C₁₀H₁₀F₃NO₂S
Molecular Weight:265.256
Hs Code.:

Synonyms:2-Amino-3-(4-trifluoromethylsulfanyl-phenyl)-propionic acid

Suppliers and Price of 2-Amino-3-(4-trifluoromethylsulfanyl-phenyl)-propionic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-Amino-3-(4-trifluoromethylsulfanyl-phenyl)-propionic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-Amino-3-(4-trifluoromethylsulfanyl-phenyl)-propionic acid

There total 4 articles about 2-Amino-3-(4-trifluoromethylsulfanyl-phenyl)-propionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 21101-63-3
4-(trifluoromethylthio)benzyl bromide

: 81477-94-3
N-(diphenylmethylene)glycine tert-butyl ester

: 126300-91-2
2-Amino-3-(4-trifluoromethylsulfanyl-phenyl)-propionic acid

Guidance literature:: N-(diphenylmethylene)glycine tert-butyl ester; With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 1h; Inert atmosphere;

4-(trifluoromethylthio)benzyl bromide; In tetrahydrofuran; at -78 ℃; for 0.5h;

With sulfuric acid; In 1,4-dioxane; for 12h; Reflux;

Reference yield:

: 352-68-1
4-trifluoromethylthiotoluene

: 126300-91-2
2-Amino-3-(4-trifluoromethylsulfanyl-phenyl)-propionic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 76 percent / Br₂ / CCl₄ / 0.5 h / Heating; Irradiation

2: 85 percent / NaOC₂H₅ / 3.5 h / Heating

3: 1.) NaCl, H₂O, 2.) 10percent aq. KOH / 1.) DMSO, 210 deg C, 4 h, 2.) dioxane, 70 deg C, 2.5 h

With potassium hydroxide; water; bromine; sodium ethanolate; sodium chloride; In tetrachloromethane;

Reference yield:

: 126300-87-6
2-Formylamino-2-(4-trifluoromethylsulfanyl-benzyl)-malonic acid diethyl ester

: 126300-91-2
2-Amino-3-(4-trifluoromethylsulfanyl-phenyl)-propionic acid

Guidance literature:: With potassium hydroxide; water; sodium chloride; Yield given. Multistep reaction; 1.) DMSO, 210 deg C, 4 h, 2.) dioxane, 70 deg C, 2.5 h;