N-(4-(4-Amino-3-(methylsulfonyl)phenoxy)pyridin-2-yl)-2-methoxy acetamide

Base Information

Chemical Name:N-(4-(4-Amino-3-(methylsulfonyl)phenoxy)pyridin-2-yl)-2-methoxy acetamide
CAS No.:1337931-79-9
Molecular Formula:C₁₅H₁₇N₃O₅S
Molecular Weight:351.383
Hs Code.:

Synonyms:N-(4-(4-Amino-3-(methylsulfonyl)phenoxy)pyridin-2-yl)-2-methoxy acetamide

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Chemical Property of N-(4-(4-Amino-3-(methylsulfonyl)phenoxy)pyridin-2-yl)-2-methoxy acetamide

Chemical Property:

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Technology Process of N-(4-(4-Amino-3-(methylsulfonyl)phenoxy)pyridin-2-yl)-2-methoxy acetamide

There total 5 articles about N-(4-(4-Amino-3-(methylsulfonyl)phenoxy)pyridin-2-yl)-2-methoxy acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1337931-78-8
2-methoxy-N-(4-(3-(methylsulfonyl)-4-nitrophenoxy)pyridin-2-yl)acetamide

: 1337931-79-9
N-(4-(4-Amino-3-(methylsulfonyl)phenoxy)pyridin-2-yl)-2-methoxy acetamide

Guidance literature:: With hydrogen; acetic acid; palladium 10% on activated carbon; In methanol; dichloromethane; at 40 ℃; Thales H-cube;

Reference yield:

: 19798-80-2
2-Amino-4-chloropyridine

: 1337931-79-9
N-(4-(4-Amino-3-(methylsulfonyl)phenoxy)pyridin-2-yl)-2-methoxy acetamide

Guidance literature:: Multi-step reaction with 4 steps

1.1: 5 h / 165 °C

1.2: 1 h / 70 °C

1.3: 1 h / 20 °C

2.1: potassium carbonate / dimethyl sulfoxide / 36 h / 80 - 100 °C

3.1: Oxone / dichloromethane; water; methanol / 20 h / 20 °C

4.1: hydrogen; acetic acid / palladium 10% on activated carbon / dichloromethane; methanol / 40 °C / Thales H-cube

With Oxone; hydrogen; potassium carbonate; acetic acid; palladium 10% on activated carbon; In methanol; dichloromethane; water; dimethyl sulfoxide;

Reference yield:

: 1262833-13-5
N-(4-hydroxypyridin-2-yl)-2-methoxyacetamide

: 1337931-79-9
N-(4-(4-Amino-3-(methylsulfonyl)phenoxy)pyridin-2-yl)-2-methoxy acetamide

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / dimethyl sulfoxide / 36 h / 80 - 100 °C

2: Oxone / dichloromethane; water; methanol / 20 h / 20 °C

3: hydrogen; acetic acid / palladium 10% on activated carbon / dichloromethane; methanol / 40 °C / Thales H-cube

With Oxone; hydrogen; potassium carbonate; acetic acid; palladium 10% on activated carbon; In methanol; dichloromethane; water; dimethyl sulfoxide;