(S)-α-methoxy-N-<(S)-1-phenylethyl>-α-(trifluoromethyl)benzeneacetamide

Base Information

Chemical Name:(S)-α-methoxy-N-<(S)-1-phenylethyl>-α-(trifluoromethyl)benzeneacetamide
CAS No.:140632-13-9
Molecular Formula:C₁₈H₁₈F₃NO₂
Molecular Weight:337.342
Hs Code.:

Synonyms:(S)-α-methoxy-N-<(S)-1-phenylethyl>-α-(trifluoromethyl)benzeneacetamide

Suppliers and Price of (S)-α-methoxy-N-<(S)-1-phenylethyl>-α-(trifluoromethyl)benzeneacetamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-α-methoxy-N-<(S)-1-phenylethyl>-α-(trifluoromethyl)benzeneacetamide

Chemical Property:

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Technology Process of (S)-α-methoxy-N-<(S)-1-phenylethyl>-α-(trifluoromethyl)benzeneacetamide

There total 4 articles about (S)-α-methoxy-N-<(S)-1-phenylethyl>-α-(trifluoromethyl)benzeneacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 2627-86-3
(S)-1-phenyl-ethylamine

: 17257-71-5,20445-31-2,56135-03-6,81655-41-6
(S)-Mosher acid

: 140632-13-9
(S)-α-methoxy-N-<(S)-1-phenylethyl>-α-(trifluoromethyl)benzeneacetamide

Guidance literature:: With N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In chloroform-d1; for 4h;
DOI:10.1016/0040-4039(96)01617-6

Reference yield:

: 140465-10-7,140465-11-8
(S)-N-[1-(2-Bromo-phenyl)-ethyl]-3,3,3-trifluoro-2-methoxy-2-phenyl-propionamide

: 140632-13-9
(S)-α-methoxy-N-<(S)-1-phenylethyl>-α-(trifluoromethyl)benzeneacetamide

Guidance literature:: With n-butyllithium; water; Multistep reaction; 1.) hexane, THF, -100 deg C, 30 min, 2.) hexane, THF;
DOI:10.1021/ja00037a014

Reference yield:

: 20445-33-4,39637-99-5
(R)-methoxytrifluoromethylphenylacetyl chloride

: 618-36-0
rac-methylbenzylamine

: 39532-56-4
(S)-α-methoxy-N-<(R)-1-phenylethyl>-α-(trifluoromethyl)benzeneacetamide

: 140632-13-9
(S)-α-methoxy-N-<(S)-1-phenylethyl>-α-(trifluoromethyl)benzeneacetamide

Guidance literature:: With pyridine; In dichloromethane; at -20 ℃; for 12h; Title compound not separated from byproducts;
DOI:10.1016/0968-0896(96)00006-5