3-(2-chloro-6-fluorophenyl)-5-(1-(4-fluorophenyl)-5-(trifluoromethyl)-1H-pyrazol-4-yl)isoxazole

Base Information

Chemical Name:3-(2-chloro-6-fluorophenyl)-5-(1-(4-fluorophenyl)-5-(trifluoromethyl)-1H-pyrazol-4-yl)isoxazole
CAS No.:1391943-57-9
Molecular Formula:C₁₉H₉ClF₅N₃O
Molecular Weight:425.745
Hs Code.:

Synonyms:3-(2-chloro-6-fluorophenyl)-5-(1-(4-fluorophenyl)-5-(trifluoromethyl)-1H-pyrazol-4-yl)isoxazole

Suppliers and Price of 3-(2-chloro-6-fluorophenyl)-5-(1-(4-fluorophenyl)-5-(trifluoromethyl)-1H-pyrazol-4-yl)isoxazole

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-(2-chloro-6-fluorophenyl)-5-(1-(4-fluorophenyl)-5-(trifluoromethyl)-1H-pyrazol-4-yl)isoxazole

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Technology Process of 3-(2-chloro-6-fluorophenyl)-5-(1-(4-fluorophenyl)-5-(trifluoromethyl)-1H-pyrazol-4-yl)isoxazole

There total 1 articles about 3-(2-chloro-6-fluorophenyl)-5-(1-(4-fluorophenyl)-5-(trifluoromethyl)-1H-pyrazol-4-yl)isoxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

: 175137-38-9
ethyl 1-(4-fluorophenyl)-5-trifluoromethyl-4-pyrazolecarboxylate

: 1391943-60-4
(E)-1-(2-chloro-6-fluorophenyl)ethanone oxime

: 1391943-57-9
3-(2-chloro-6-fluorophenyl)-5-(1-(4-fluorophenyl)-5-(trifluoromethyl)-1H-pyrazol-4-yl)isoxazole

Guidance literature:: ethyl 1-(4-fluorophenyl)-5-trifluoromethyl-4-pyrazolecarboxylate; (E)-1-(2-chloro-6-fluorophenyl)ethanone oxime; With n-butyllithium; In tetrahydrofuran; at 0 ℃; for 0.333333h; Inert atmosphere; Cooling with ice;

With hydrogenchloride; In tetrahydrofuran; water; for 1h; Reflux;