4-[(E)-(6-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-hydroxymethyl]-benzenepropanoic acid ethyl ester

Base Information

Chemical Name:4-[(E)-(6-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-hydroxymethyl]-benzenepropanoic acid ethyl ester
CAS No.:1174179-92-0
Molecular Formula:C₂₀H₁₈FNO₄
Molecular Weight:355.366
Hs Code.:

Synonyms:4-[(E)-(6-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-hydroxymethyl]-benzenepropanoic acid ethyl ester

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Chemical Property of 4-[(E)-(6-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-hydroxymethyl]-benzenepropanoic acid ethyl ester

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Technology Process of 4-[(E)-(6-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-hydroxymethyl]-benzenepropanoic acid ethyl ester

There total 1 articles about 4-[(E)-(6-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-hydroxymethyl]-benzenepropanoic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 1174179-94-2
4-[(E)-(1-acetyl-6-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydroxymethyl]-benzenepropanoic acid ethyl ester

: 1174179-92-0
4-[(E)-(6-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-hydroxymethyl]-benzenepropanoic acid ethyl ester

Guidance literature:: 4-[(E)-(1-acetyl-6-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydroxymethyl]-benzenepropanoic acid ethyl ester; With sodium methylate; In methanol; for 1h; Reflux;

With hydrogenchloride; In methanol; water; at 15 ℃;