tert-butyl (2-((2-((5-carbamoyl-2-methylphenyl)amino)-5-(trifluoromethyl) pyrimidin-4-yl)amino)phenyl)carbamate

Base Information

Chemical Name:tert-butyl (2-((2-((5-carbamoyl-2-methylphenyl)amino)-5-(trifluoromethyl) pyrimidin-4-yl)amino)phenyl)carbamate
CAS No.:1622003-25-1
Molecular Formula:C₂₄H₂₅F₃N₆O₃
Molecular Weight:502.496
Hs Code.:

Synonyms:tert-butyl (2-((2-((5-carbamoyl-2-methylphenyl)amino)-5-(trifluoromethyl) pyrimidin-4-yl)amino)phenyl)carbamate

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Chemical Property of tert-butyl (2-((2-((5-carbamoyl-2-methylphenyl)amino)-5-(trifluoromethyl) pyrimidin-4-yl)amino)phenyl)carbamate

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Technology Process of tert-butyl (2-((2-((5-carbamoyl-2-methylphenyl)amino)-5-(trifluoromethyl) pyrimidin-4-yl)amino)phenyl)carbamate

There total 1 articles about tert-butyl (2-((2-((5-carbamoyl-2-methylphenyl)amino)-5-(trifluoromethyl) pyrimidin-4-yl)amino)phenyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1622003-25-1
tert-butyl (2-((2-((5-carbamoyl-2-methylphenyl)amino)-5-(trifluoromethyl) pyrimidin-4-yl)amino)phenyl)carbamate

Guidance literature:: With toluene-4-sulfonic acid; In 1,4-dioxane; at 20 ℃; for 16h;

Reference yield:

: 1622003-25-1
tert-butyl (2-((2-((5-carbamoyl-2-methylphenyl)amino)-5-(trifluoromethyl) pyrimidin-4-yl)amino)phenyl)carbamate

: 1622003-26-2
C₁₉H₁₇F₃N₆O

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 2h;

Reference yield:

: 1622003-25-1
tert-butyl (2-((2-((5-carbamoyl-2-methylphenyl)amino)-5-(trifluoromethyl) pyrimidin-4-yl)amino)phenyl)carbamate

: 1621999-56-1
3-(4-(2-acrylamidophenylamino)-5-(trifluoromethyl)pyrimidin-2-ylamino)-4-methylbenzamide

Guidance literature:: Multi-step reaction with 2 steps

1: trifluoroacetic acid / dichloromethane / 2 h / 20 °C

2: dichloromethane; tetrahydrofuran / 2 h / -78 °C

With trifluoroacetic acid; In tetrahydrofuran; dichloromethane;