methyl 2-hydroxy-3-(2-(3,4-dimethoxyphenyl)ethoxy)-3,3-di-(4-ethyl-phenyl)propionate

Base Information

Chemical Name:methyl 2-hydroxy-3-(2-(3,4-dimethoxyphenyl)ethoxy)-3,3-di-(4-ethyl-phenyl)propionate
CAS No.:204268-07-5
Molecular Formula:C₃₀H₃₆O₆
Molecular Weight:492.612
Hs Code.:

Synonyms:methyl 2-hydroxy-3-(2-(3,4-dimethoxyphenyl)ethoxy)-3,3-di-(4-ethyl-phenyl)propionate

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Chemical Property of methyl 2-hydroxy-3-(2-(3,4-dimethoxyphenyl)ethoxy)-3,3-di-(4-ethyl-phenyl)propionate

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Technology Process of methyl 2-hydroxy-3-(2-(3,4-dimethoxyphenyl)ethoxy)-3,3-di-(4-ethyl-phenyl)propionate

There total 1 articles about methyl 2-hydroxy-3-(2-(3,4-dimethoxyphenyl)ethoxy)-3,3-di-(4-ethyl-phenyl)propionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3,3-bis-(4-ethylphenyl)oxirane-2-carboxylic acid methyl ester

: 7417-21-2
2-(3,4-dimethoxyphenyl)ethyl alcohol

: 204268-07-5
methyl 2-hydroxy-3-(2-(3,4-dimethoxyphenyl)ethoxy)-3,3-di-(4-ethyl-phenyl)propionate

Guidance literature:: With boron trifluoride diethyl etherate; In dichloromethane; for 2h; Ambient temperature;
DOI:10.1021/jm9910425

Reference yield: 71.0%

: 204268-07-5
methyl 2-hydroxy-3-(2-(3,4-dimethoxyphenyl)ethoxy)-3,3-di-(4-ethyl-phenyl)propionate

: 204268-08-6
2-hydroxy-3-(2-(3,4-dimethoxyphenyl)ethoxy)-3,3-di(4-ethylphenyl)propionic acid

Guidance literature:: methyl 2-hydroxy-3-(2-(3,4-dimethoxyphenyl)ethoxy)-3,3-di-(4-ethyl-phenyl)propionate; With sodium hydroxide; In 1,4-dioxane; water; at 60 ℃; for 3h;

With hydrogenchloride; In water;

Reference yield:

: 204268-07-5
methyl 2-hydroxy-3-(2-(3,4-dimethoxyphenyl)ethoxy)-3,3-di-(4-ethyl-phenyl)propionate

: 3-<2-(3,4-dimethoxyphenyl)ethoxy>-2-<(4-methoxy-6-methylpyrimidin-2-yl)oxy>-3,3-bis-(4-ethylphenyl)propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 1 N aq. NaOH / dioxane / 2 h / 80 °C

2: LiNH₂ / dimethylformamide / 18 h / Ambient temperature

With sodium hydroxide; lithium amide; In 1,4-dioxane; N,N-dimethyl-formamide;
DOI:10.1021/jm9910425