7-(4-methyl-1H-imidazol-1-yl)-2-({(2S,4S,5R)-4-methyl-5-[4-(trifluoromethyl)phenyl]tetrahydrofuran-2-yl}methyl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-dione, trifluoroacetate salt

Base Information

Chemical Name:7-(4-methyl-1H-imidazol-1-yl)-2-({(2S,4S,5R)-4-methyl-5-[4-(trifluoromethyl)phenyl]tetrahydrofuran-2-yl}methyl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-dione, trifluoroacetate salt
CAS No.:1587726-76-8
Molecular Formula:C₂HF₃O₂*C₂₅H₂₅F₃N₄O₃
Molecular Weight:600.518
Hs Code.:

7-(4-methyl-1H-imidazol-1-yl)-2-({(2S,4S,5R)-4-methyl-5-[4-(trifluoromethyl)phenyl]tetrahydrofuran-2-yl}methyl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-dione, trifluoroacetate salt

Synonyms:7-(4-methyl-1H-imidazol-1-yl)-2-({(2S,4S,5R)-4-methyl-5-[4-(trifluoromethyl)phenyl]tetrahydrofuran-2-yl}methyl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-dione, trifluoroacetate salt

Suppliers and Price of 7-(4-methyl-1H-imidazol-1-yl)-2-({(2S,4S,5R)-4-methyl-5-[4-(trifluoromethyl)phenyl]tetrahydrofuran-2-yl}methyl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-dione, trifluoroacetate salt

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 7-(4-methyl-1H-imidazol-1-yl)-2-({(2S,4S,5R)-4-methyl-5-[4-(trifluoromethyl)phenyl]tetrahydrofuran-2-yl}methyl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-dione, trifluoroacetate salt

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 7-(4-methyl-1H-imidazol-1-yl)-2-({(2S,4S,5R)-4-methyl-5-[4-(trifluoromethyl)phenyl]tetrahydrofuran-2-yl}methyl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-dione, trifluoroacetate salt

There total 3 articles about 7-(4-methyl-1H-imidazol-1-yl)-2-({(2S,4S,5R)-4-methyl-5-[4-(trifluoromethyl)phenyl]tetrahydrofuran-2-yl}methyl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-dione, trifluoroacetate salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1587727-51-2
7-(4-methyl-1H-imidazol-1-yl)-2-(prop-2-en-1-yl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-dione

: 1587726-76-8
7-(4-methyl-1H-imidazol-1-yl)-2-({(2S,4S,5R)-4-methyl-5-[4-(trifluoromethyl)phenyl]tetrahydrofuran-2-yl}methyl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-dione, trifluoroacetate salt

Guidance literature:: With trifluoroacetic acid; In water; acetonitrile;

Reference yield:

: 1262197-81-8
methyl 6-methoxy-5-(4-methyl-1H-imidazol-1-yl)pyridine-2-carboxylate

: 1587726-76-8
7-(4-methyl-1H-imidazol-1-yl)-2-({(2S,4S,5R)-4-methyl-5-[4-(trifluoromethyl)phenyl]tetrahydrofuran-2-yl}methyl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-dione, trifluoroacetate salt

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogen bromide / acetic acid

2: ammonia; N-ethyl-N,N-diisopropylamine / methanol; dichloromethane; chloroform

3: trifluoroacetic acid / water; acetonitrile

With ammonia; hydrogen bromide; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In methanol; dichloromethane; chloroform; water; acetic acid; acetonitrile;

Reference yield:

: 5-(4-methyl-1H-imidazol-1-yl)-6-oxo-1,6-dihydropyridine-2-carboxylic acid, hydrobromide salt

: 1587726-76-8
7-(4-methyl-1H-imidazol-1-yl)-2-({(2S,4S,5R)-4-methyl-5-[4-(trifluoromethyl)phenyl]tetrahydrofuran-2-yl}methyl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-dione, trifluoroacetate salt

Guidance literature:: Multi-step reaction with 2 steps

1: ammonia; N-ethyl-N,N-diisopropylamine / methanol; dichloromethane; chloroform

2: trifluoroacetic acid / water; acetonitrile

With ammonia; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In methanol; dichloromethane; chloroform; water; acetonitrile;