2-(4-benzhydryl-1-piperazinylmethyl)-6-methoxy-1,2,3,4-tetrahydro-1-naphthalenol

Base Information

Chemical Name:2-(4-benzhydryl-1-piperazinylmethyl)-6-methoxy-1,2,3,4-tetrahydro-1-naphthalenol
CAS No.:65472-83-5
Molecular Formula:C₂₉H₃₄N₂O₂
Molecular Weight:442.601
Hs Code.:

Synonyms:2-(4-benzhydryl-1-piperazinylmethyl)-6-methoxy-1,2,3,4-tetrahydro-1-naphthalenol

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(4-benzhydryl-1-piperazinylmethyl)-6-methoxy-1,2,3,4-tetrahydro-1-naphthalenol

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Technology Process of 2-(4-benzhydryl-1-piperazinylmethyl)-6-methoxy-1,2,3,4-tetrahydro-1-naphthalenol

There total 4 articles about 2-(4-benzhydryl-1-piperazinylmethyl)-6-methoxy-1,2,3,4-tetrahydro-1-naphthalenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 65472-76-6
2-(4-benzhydryl-piperazin-1-ylmethyl)-6-methoxy-3,4-dihydro-2H-naphthalen-1-one

: 3-(4-benzhydryl-1-piperazinylmethyl)-7-methoxy-1,2-dihydronaphthalene hydrochloride

: 65472-83-5
2-(4-benzhydryl-1-piperazinylmethyl)-6-methoxy-1,2,3,4-tetrahydro-1-naphthalenol

Guidance literature:: With sodium borohydrid; In methanol; chloroform; water;

Reference yield:

: 65472-76-6
2-(4-benzhydryl-piperazin-1-ylmethyl)-6-methoxy-3,4-dihydro-2H-naphthalen-1-one

: 65472-83-5
2-(4-benzhydryl-1-piperazinylmethyl)-6-methoxy-1,2,3,4-tetrahydro-1-naphthalenol

Guidance literature:: With sodium tetrahydroborate; In methanol; chloroform; for 0.5h; Ambient temperature;
DOI:10.1248/cpb.31.2006

Reference yield:

: 56609-03-1,57311-01-0,66090-75-3
N-benzhydrylpiperazine hydrochloride

: 65472-83-5
2-(4-benzhydryl-1-piperazinylmethyl)-6-methoxy-1,2,3,4-tetrahydro-1-naphthalenol

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / ethanol / Ambient temperature

2: NaBH₄ / methanol; CHCl₃ / 0.5 h / Ambient temperature

With sodium tetrahydroborate; In methanol; ethanol; chloroform;
DOI:10.1248/cpb.31.2006