triphenylphosphonium [α-(1-adamantanylacetyl)-α-ethoxycarbonyl]methylide

Base Information

Chemical Name:triphenylphosphonium [α-(1-adamantanylacetyl)-α-ethoxycarbonyl]methylide
CAS No.:455333-75-2
Molecular Formula:C₃₄H₃₇O₃P
Molecular Weight:524.64
Hs Code.:

Synonyms:triphenylphosphonium [α-(1-adamantanylacetyl)-α-ethoxycarbonyl]methylide

Suppliers and Price of triphenylphosphonium [α-(1-adamantanylacetyl)-α-ethoxycarbonyl]methylide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of triphenylphosphonium [α-(1-adamantanylacetyl)-α-ethoxycarbonyl]methylide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of triphenylphosphonium [α-(1-adamantanylacetyl)-α-ethoxycarbonyl]methylide

There total 2 articles about triphenylphosphonium [α-(1-adamantanylacetyl)-α-ethoxycarbonyl]methylide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 19835-38-2
1-adamantylacetyl chloride

: 1099-45-2
ethyl (triphenylphosphoranylidene)acetate

: 455333-75-2
triphenylphosphonium [α-(1-adamantanylacetyl)-α-ethoxycarbonyl]methylide

Guidance literature:: In benzene; at 20 ℃;
DOI:10.1023/A:1015501313852

Reference yield:

: 4942-47-6
(adamant-1-yl)-acetic acid

: 1099-45-2
ethyl (triphenylphosphoranylidene)acetate

: 455333-75-2
triphenylphosphonium [α-(1-adamantanylacetyl)-α-ethoxycarbonyl]methylide

Guidance literature:: With dmap; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In dichloromethane; at 0 - 20 ℃;
DOI:10.1021/jm049069y

Reference yield:

: 455333-75-2
triphenylphosphonium [α-(1-adamantanylacetyl)-α-ethoxycarbonyl]methylide

: 3-[(5-adamantan-1-ylmethyl-2-o-tolyl-1H-imidazole-4-carbonyl)-amino]-benzoic acid

Guidance literature:: Multi-step reaction with 5 steps

1: OXONE / tetrahydrofuran / 20 °C

2: NH₄OAc; AcOH / 70 °C

3: aq. NaOH / ethanol / Heating

4: 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride; 4-(dimethylamino)pyridine; 1-hydroxybenzotriazole / dimethylformamide / 20 °C

5: H₂ / Pd/C / tetrahydrofuran; methanol

With dmap; Oxone; sodium hydroxide; ammonium acetate; hydrogen; benzotriazol-1-ol; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; palladium on activated charcoal; In tetrahydrofuran; methanol; ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jm0490686