Boc-(S)-alpha-allyl-proline

Base Information

Chemical Name:Boc-(S)-alpha-allyl-proline
CAS No.:706806-59-9
Molecular Formula:C₁₃H₂₁NO₄
Molecular Weight:255.314
Hs Code.:2933990090
European Community (EC) Number:634-739-0
DSSTox Substance ID:DTXSID30428036
Nikkaji Number:J1.945.756G
Wikidata:Q82240806
Mol file:706806-59-9.mol

Synonyms:706806-59-9;Boc-(S)-alpha-allyl-proline;(S)-2-Allyl-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid;(2S)-1-[(2-methylpropan-2-yl)oxycarbonyl]-2-prop-2-enylpyrrolidine-2-carboxylic acid;Boc-(S)-alpha-allylproline;(S)-2-Allyl-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester;Boc-(S)-a-allylproline;Boc-alpha-allyl-D-proline;SCHEMBL7264298;BOC-(S)--ALLYL-PRO-OH;Boc-(S)- alpha -allyl-Pro-OH;DTXSID30428036;(S)-2-Allyl-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylicacid;MFCD06659382;AKOS016844110;(2S)-1-[(2-methylpropan-2-yl)oxy-oxomethyl]-2-prop-2-enyl-2-pyrrolidinecarboxylic acid;PS-12639;Boc-(S)-alpha-allyl-Pro-OH, >=98.0%;CS-0110096;D76974;(2S)-1-Boc-2-allyl-pyrrolidine-2-carboxylic acid;(2S)-1-(tert-Butoxycarbonyl)-2-allyl-2-pyrrolidinecarboxylic acid;(2S)-1-[(tert-butoxy)carbonyl]-2-(prop-2-en-1-yl)pyrrolidine-2-carboxylic acid

Suppliers and Price of Boc-(S)-alpha-allyl-proline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(S)-2-ALLYL-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 95.00%
500MG
$ 957.46

Biosynth Carbosynth
Boc-(S)-alpha-allylproline
5 mg
$ 50.00

Biosynth Carbosynth
Boc-(S)-alpha-allylproline
10 mg
$ 80.00

Biosynth Carbosynth
Boc-(S)-alpha-allylproline
25 mg
$ 125.00

Biosynth Carbosynth
Boc-(S)-alpha-allylproline
50 mg
$ 200.00

Biosynth Carbosynth
Boc-(S)-alpha-allylproline
100 mg
$ 300.00

Chemenu
(S)-2-allyl-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylicacid 95%
1g
$ 705.00

Crysdot
(S)-2-Allyl-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylicacid 95+%
1g
$ 747.00

Crysdot
(S)-2-Allyl-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylicacid 95+%
5g
$ 3006.00

Sigma-Aldrich
Boc-(S)-α-allyl-Pro-OH ≥98.0%
500 mg
$ 325.00

Total 11 raw suppliers

Chemical Property of Boc-(S)-alpha-allyl-proline

Chemical Property:

Vapor Pressure:2.67E-06mmHg at 25°C
Refractive Index:1.498
Boiling Point:364.3°C at 760 mmHg
PKA:4.02±0.20(Predicted)
Flash Point:174.1°C
PSA：66.84000
Density:1.125g/cm³
LogP:2.35470
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:255.14705815
Heavy Atom Count:18
Complexity:359

Purity/Quality:

97% ^*data from raw suppliers

(S)-2-ALLYL-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCCC1(CC=C)C(=O)O
Isomeric SMILES:CC(C)(C)OC(=O)N1CCC[C@]1(CC=C)C(=O)O
Uses Boc-(S)-alpha-allylproline

Technology Process of Boc-(S)-alpha-allyl-proline

There total 4 articles about Boc-(S)-alpha-allyl-proline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 195833-47-7
(S)-2-Allyl-pyrrolidine-2-carboxylic acid

: 706806-59-9
(S)-N-Boc-2-allylproline

Guidance literature:: With sodium hydroxide; In 1,4-dioxane; at 20 ℃; for 24h;
DOI:10.1248/cpb.47.983

Reference yield:

: 946075-02-1
C₁₉H₃₅NO₄Si

: 706806-59-9
(S)-N-Boc-2-allylproline

Guidance literature:: Multi-step reaction with 3 steps

1: 100 percent / diethyl ether

2: 100 percent / HBF₄ / dioxane / 3 h / 100 °C

3: Na₂CO₃ / dioxane; H₂O / 2 h / 20 °C

With tetrafluoroboric acid; sodium carbonate; In 1,4-dioxane; diethyl ether; water;
DOI:10.1016/j.tetlet.2007.05.066

Reference yield:

: 946075-04-3
C₂₀H₃₇NO₄Si

: 706806-59-9
(S)-N-Boc-2-allylproline

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / HBF₄ / dioxane / 3 h / 100 °C

2: Na₂CO₃ / dioxane; H₂O / 2 h / 20 °C

With tetrafluoroboric acid; sodium carbonate; In 1,4-dioxane; water;
DOI:10.1016/j.tetlet.2007.05.066