C₂₉H₃₄FNO₃Si

Base Information Edit

Chemical Name:C₂₉H₃₄FNO₃Si
CAS No.:1403338-27-1
Molecular Formula:C₂₉H₃₄FNO₃Si
Molecular Weight:491.678
Hs Code.:
Mol file:1403338-27-1.mol

C<sub>29</sub>H<sub>34</sub>FNO<sub>3</sub>Si

Synonyms:C₂₉H₃₄FNO₃Si

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Chemical Property of C₂₉H₃₄FNO₃Si Edit

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Technology Process of C₂₉H₃₄FNO₃Si

There total 4 articles about C₂₉H₃₄FNO₃Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1403338-21-5
(3S,4E)-5-[2-cyclopropyl-4-(4-fluorophenyl)quinoline-3-yl]-3-hydroxypentenoic acid (R)-α-methylbenzylamine salt

: 1403338-27-1
C₂₉H₃₄FNO₃Si

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrogenchloride; water / dichloromethane / 0 - 30 °C / pH 2 - 2.5

2.1: potassium iodide / N,N-dimethyl-formamide / 0.75 h / 25 - 65 °C / Inert atmosphere

2.2: 0.5 h / 60 - 65 °C

2.3: 0.5 h / 60 - 65 °C

With hydrogenchloride; water; potassium iodide; In dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 1403338-20-4
(1S)-2-hydroxy-1,2,2-triphenylethyl (4E)-5-[2-cyclopropyl-4-(4-fluorophenyl)quinoline-3-yl]-3-hydroxy-4-pentenoate

: 1403338-27-1
C₂₉H₃₄FNO₃Si

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydroxide; water / tetrahydrofuran / 24 h / 20 - 30 °C

1.2: pH 1.5 - 2

1.3: 20 °C

2.1: hydrogenchloride; water / dichloromethane / 0 - 30 °C / pH 2 - 2.5

3.1: potassium iodide / N,N-dimethyl-formamide / 0.75 h / 25 - 65 °C / Inert atmosphere

3.2: 0.5 h / 60 - 65 °C

3.3: 0.5 h / 60 - 65 °C

With hydrogenchloride; water; potassium iodide; sodium hydroxide; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 148901-68-2,121660-63-7
(E)-3-[2-cyclopropyl-4-(4-fluoro-phenyl)-quinolin-3-yl]-propenal

: 1403338-27-1
C₂₉H₃₄FNO₃Si

Guidance literature:: Multi-step reaction with 4 steps

1.1: lithium hexamethyldisilazane / hexane; tetrahydrofuran / 1 h / -35 - -15 °C

1.2: 1 h / -80 - -75 °C

2.1: sodium hydroxide; water / tetrahydrofuran / 24 h / 20 - 30 °C

2.2: pH 1.5 - 2

2.3: 20 °C

3.1: hydrogenchloride; water / dichloromethane / 0 - 30 °C / pH 2 - 2.5

4.1: potassium iodide / N,N-dimethyl-formamide / 0.75 h / 25 - 65 °C / Inert atmosphere

4.2: 0.5 h / 60 - 65 °C

4.3: 0.5 h / 60 - 65 °C

With hydrogenchloride; water; potassium iodide; sodium hydroxide; lithium hexamethyldisilazane; In tetrahydrofuran; hexane; dichloromethane; N,N-dimethyl-formamide;