tert-butyl (5-{2-[5-(5-chloro-2-methylphenyl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl]-1,3-thiazol-5-yl}-2H-tetrazol-2-yl)acetate

Base Information

Chemical Name:tert-butyl (5-{2-[5-(5-chloro-2-methylphenyl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl]-1,3-thiazol-5-yl}-2H-tetrazol-2-yl)acetate
CAS No.:1246749-75-6
Molecular Formula:C₂₃H₂₈ClN₇O₂S
Molecular Weight:502.04
Hs Code.:

Synonyms:tert-butyl (5-{2-[5-(5-chloro-2-methylphenyl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl]-1,3-thiazol-5-yl}-2H-tetrazol-2-yl)acetate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of tert-butyl (5-{2-[5-(5-chloro-2-methylphenyl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl]-1,3-thiazol-5-yl}-2H-tetrazol-2-yl)acetate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of tert-butyl (5-{2-[5-(5-chloro-2-methylphenyl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl]-1,3-thiazol-5-yl}-2H-tetrazol-2-yl)acetate

There total 1 articles about tert-butyl (5-{2-[5-(5-chloro-2-methylphenyl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl]-1,3-thiazol-5-yl}-2H-tetrazol-2-yl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1241897-92-6
tert-butyl [5-(2-bromo-1,3-thiazol-5-yl)-2H-tetrazol-2-yl]acetate

: 2-(5-chloro-2-methylphenyl)octahydropyrrolo[3,4-c]pyrrole hydrochloride

: 1246749-75-6
tert-butyl (5-{2-[5-(5-chloro-2-methylphenyl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl]-1,3-thiazol-5-yl}-2H-tetrazol-2-yl)acetate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In 1-methyl-pyrrolidin-2-one; at 110 ℃; for 17h;

Reference yield:

: 1246749-75-6
tert-butyl (5-{2-[5-(5-chloro-2-methylphenyl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl]-1,3-thiazol-5-yl}-2H-tetrazol-2-yl)acetate

: 1246749-01-8
(5-{2-[5-(5-chloro-2-methylphenyl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl]-1,3-thiazol-5-yl}-2H-tetrazol-2-yl)acetic acid

Guidance literature:: tert-butyl (5-{2-[5-(5-chloro-2-methylphenyl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl]-1,3-thiazol-5-yl}-2H-tetrazol-2-yl)acetate; With water; lithium hydroxide; In tetrahydrofuran; methanol; at 20 ℃; for 16h;

With hydrogenchloride; In tetrahydrofuran; methanol; water; ethyl acetate;