trichloroacetamido (2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-benzoyl-thio-β-D-galactopyranoside

Base Information

• Chemical Name: trichloroacetamido (2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-benzoyl-thio-β-D-galactopyranoside
• CAS No.: 221623-56-9
• Molecular Formula: C₄₃H₄₂Cl₃NO₁₈
• Molecular Weight: 967.161
• Mol file: 221623-56-9.mol

Synonyms:trichloroacetamido (2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-benzoyl-thio-β-D-galactopyranoside

Chemical Property of trichloroacetamido (2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-benzoyl-thio-β-D-galactopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trichloroacetamido (2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-benzoyl-thio-β-D-galactopyranoside

There total 3 articles about trichloroacetamido (2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-benzoyl-thio-β-D-galactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-methoxyphenyl (2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-benzoyl-β-D-galactopyranoside (312957-75-8) → trichloroacetamido (2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-benzoyl-thio-β-D-galactopyranoside (221623-56-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 90 percent / BF₃*Et₂O / CH₂Cl₂ / 84 h / 60 °C

2: N-bromosuccinimide / H₂O / 1 h

3: CH₂Cl₂ / 1 h / 0 °C

With N-Bromosuccinimide; boron trifluoride diethyl etherate; In dichloromethane; water; 1: Substitution / 2: Substitution / 3: Substitution;

DOI:10.1016/S0008-6215(00)00154-3

Reference yield:

4-methylphenyl (2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-benzoyl-1-thio-β-D-galactopyranoside (312957-61-2) → trichloroacetamido (2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-benzoyl-thio-β-D-galactopyranoside (221623-56-9)

Guidance literature:

Multi-step reaction with 2 steps

1: N-bromosuccinimide / H₂O / 1 h

2: CH₂Cl₂ / 1 h / 0 °C

With N-Bromosuccinimide; In dichloromethane; water; 1: Substitution / 2: Substitution;

DOI:10.1016/S0008-6215(00)00154-3

Reference yield:

trichloroacetonitrile (545-06-2) + C44H48O19 → trichloroacetamido (2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-benzoyl-thio-β-D-galactopyranoside (221623-56-9)

Guidance literature:

In dichloromethane; at 0 ℃; for 1h;

DOI:10.1016/S0008-6215(00)00154-3

upstream raw materials:

trichloroacetonitrile

4-methoxyphenyl (2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-benzoyl-β-D-galactopyranoside

4-methylphenyl (2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-benzoyl-1-thio-β-D-galactopyranoside