C₁₃H₁₆O₄

Base Information

• Chemical Name: C₁₃H₁₆O₄
• CAS No.: 1276019-90-9
• Molecular Formula: C₁₃H₁₆O₄
• Molecular Weight: 236.268
• Mol file: 1276019-90-9.mol

Synonyms:C₁₃H₁₆O₄

Chemical Property of C₁₃H₁₆O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₃H₁₆O₄

There total 3 articles about C₁₃H₁₆O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

C17H24O4 (1276019-91-0) → C13H16O4 (1276019-90-9)

Guidance literature:

C₁₇H₂₄O₄; With potassium hydroxide; In ethanol; for 12h; Reflux;

With hydrogenchloride; In water;

DOI:10.1016/j.bmcl.2010.12.101

Reference yield:

C14H20O4 (1276019-92-1) → C13H16O4 (1276019-90-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: lithium diisopropyl amide / tetrahydrofuran / 1 h / -78 °C

1.2: 2 h / -78 - 20 °C

2.1: potassium hydroxide / ethanol / 12 h / Reflux

With potassium hydroxide; lithium diisopropyl amide; In tetrahydrofuran; ethanol;

DOI:10.1016/j.bmcl.2010.12.101

Reference yield:

2-bromo-1,5-dimethoxy-3-methylbenzene (13321-73-8) → C13H16O4 (1276019-90-9)

Guidance literature:

Multi-step reaction with 3 steps

1.1: n-butyllithium / tetrahydrofuran / 1 h / -78 °C

1.2: 2 h / -78 - 20 °C

2.1: lithium diisopropyl amide / tetrahydrofuran / 1 h / -78 °C

2.2: 2 h / -78 - 20 °C

3.1: potassium hydroxide / ethanol / 12 h / Reflux

With n-butyllithium; potassium hydroxide; lithium diisopropyl amide; In tetrahydrofuran; ethanol;

DOI:10.1016/j.bmcl.2010.12.101

upstream raw materials:

C₁₄H₂₀O₄

C₁₇H₂₄O₄

2-bromo-1,5-dimethoxy-3-methylbenzene

Downstream raw materials:

C₂₀H₂₈O₄