Technology Process of [1,3]dioxolo[7,8-g]-2-phenyl-1,2,3,4-tetrahydroisoquinoline
There total 4 articles about [1,3]dioxolo[7,8-g]-2-phenyl-1,2,3,4-tetrahydroisoquinoline which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium phosphate; copper(l) iodide; ethylene glycol;
In
isopropyl alcohol;
at 20 - 90 ℃;
Inert atmosphere;
DOI:10.1039/c1cc15050b
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: ammonium acetate / acetic acid / 1.5 h / 20 °C / Reflux
2.1: lithium aluminium tetrahydride / tetrahydrofuran / 4 h / Reflux
3.1: formic acid / 0.17 h / 0 °C
3.2: 24 h / 50 °C
4.1: copper(l) iodide; potassium phosphate; ethylene glycol / isopropyl alcohol / 20 - 90 °C / Inert atmosphere
With
potassium phosphate; copper(l) iodide; lithium aluminium tetrahydride; formic acid; ammonium acetate; ethylene glycol;
In
tetrahydrofuran; acetic acid; isopropyl alcohol;
DOI:10.1039/c1cc15050b
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: lithium aluminium tetrahydride / tetrahydrofuran / 4 h / Reflux
2.1: formic acid / 0.17 h / 0 °C
2.2: 24 h / 50 °C
3.1: copper(l) iodide; potassium phosphate; ethylene glycol / isopropyl alcohol / 20 - 90 °C / Inert atmosphere
With
potassium phosphate; copper(l) iodide; lithium aluminium tetrahydride; formic acid; ethylene glycol;
In
tetrahydrofuran; isopropyl alcohol;
DOI:10.1039/c1cc15050b
