ethyl-3-(4-bromophenyl)-2-((tert-butoxycarbonyl)amino)-3-oxopropanoate

Base Information

Chemical Name:ethyl-3-(4-bromophenyl)-2-((tert-butoxycarbonyl)amino)-3-oxopropanoate
CAS No.:1255203-02-1
Molecular Formula:C₁₆H₂₀BrNO₅
Molecular Weight:386.243
Hs Code.:

Synonyms:ethyl-3-(4-bromophenyl)-2-((tert-butoxycarbonyl)amino)-3-oxopropanoate

Suppliers and Price of ethyl-3-(4-bromophenyl)-2-((tert-butoxycarbonyl)amino)-3-oxopropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl-3-(4-bromophenyl)-2-((tert-butoxycarbonyl)amino)-3-oxopropanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl-3-(4-bromophenyl)-2-((tert-butoxycarbonyl)amino)-3-oxopropanoate

There total 2 articles about ethyl-3-(4-bromophenyl)-2-((tert-butoxycarbonyl)amino)-3-oxopropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 137686-07-8,137401-45-7
2-{[(tert-butoxy)carbonyl]amino}-3-ethoxy-3-oxopropanoic acid

: 586-75-4
4-chlorobenzoyl chloride

: 1255203-02-1
ethyl-3-(4-bromophenyl)-2-((tert-butoxycarbonyl)amino)-3-oxopropanoate

Guidance literature:: 2-{[(tert-butoxy)carbonyl]amino}-3-ethoxy-3-oxopropanoic acid; With triethylamine; magnesium chloride; In tetrahydrofuran; at 0 ℃; for 2h;

4-chlorobenzoyl chloride; In tetrahydrofuran; at 0 - 20 ℃;
DOI:10.1021/ol102323k

Reference yield:

: 102831-44-7
diethyl tert-butoxycarbonylaminomalonate

: 1255203-02-1
ethyl-3-(4-bromophenyl)-2-((tert-butoxycarbonyl)amino)-3-oxopropanoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydroxide

2.1: triethylamine; magnesium chloride / tetrahydrofuran / 2 h / 0 °C

2.2: 0 - 20 °C

With triethylamine; sodium hydroxide; magnesium chloride; In tetrahydrofuran;
DOI:10.1002/chem.201103739

Reference yield: 81.0%

: 1255203-02-1
ethyl-3-(4-bromophenyl)-2-((tert-butoxycarbonyl)amino)-3-oxopropanoate

: 1255203-10-1
(2S,3S)-ethyl-3-(4-bromophenyl)-2-((tert-butoxycarbonyl)amino)-3-hydroxypropanoate

Guidance literature:: With dichloro(benzene)ruthenium(II) dimer; triethylammonium formate; (1S,2S)-2-(benzylamino)-1,2-diphenylethanol; In isopropyl alcohol; at 20 ℃; for 168h; optical yield given as %ee; enantioselective reaction;
DOI:10.1021/ol102323k