(4R,5S,6S,7S)-1,6-bis(tert-butyldimethylsilanyloxy)-5,7-dimethylnon-8-en-4-yl 4-methoxybenzyl ether

Base Information

Chemical Name:(4R,5S,6S,7S)-1,6-bis(tert-butyldimethylsilanyloxy)-5,7-dimethylnon-8-en-4-yl 4-methoxybenzyl ether
CAS No.:623926-33-0
Molecular Formula:C₃₁H₅₈O₄Si₂
Molecular Weight:550.97
Hs Code.:

Synonyms:(4R,5S,6S,7S)-1,6-bis(tert-butyldimethylsilanyloxy)-5,7-dimethylnon-8-en-4-yl 4-methoxybenzyl ether

Suppliers and Price of (4R,5S,6S,7S)-1,6-bis(tert-butyldimethylsilanyloxy)-5,7-dimethylnon-8-en-4-yl 4-methoxybenzyl ether

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (4R,5S,6S,7S)-1,6-bis(tert-butyldimethylsilanyloxy)-5,7-dimethylnon-8-en-4-yl 4-methoxybenzyl ether

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (4R,5S,6S,7S)-1,6-bis(tert-butyldimethylsilanyloxy)-5,7-dimethylnon-8-en-4-yl 4-methoxybenzyl ether

There total 5 articles about (4R,5S,6S,7S)-1,6-bis(tert-butyldimethylsilanyloxy)-5,7-dimethylnon-8-en-4-yl 4-methoxybenzyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 89238-99-3
O-(4-methoxybenzyl)-trichloroacetimidate

: 623926-31-8
(4R,5S,6S,7S)-1,6-bis(tert-butyldimethylsilanyloxy)-5,7-dimethylnon-8-en-4-ol

: 623926-33-0
(4R,5S,6S,7S)-1,6-bis(tert-butyldimethylsilanyloxy)-5,7-dimethylnon-8-en-4-yl 4-methoxybenzyl ether

Guidance literature:: With trifluorormethanesulfonic acid; In diethyl ether; at 20 ℃; for 72h;
DOI:10.1016/S0968-0896(03)00186-X

Reference yield:

: 106296-58-6
(2S,3S,4S)-(1-tert-butyldimethylsilanyloxy)-2,4-dimethylhex-5-en-3-ol

: 623926-33-0
(4R,5S,6S,7S)-1,6-bis(tert-butyldimethylsilanyloxy)-5,7-dimethylnon-8-en-4-yl 4-methoxybenzyl ether

Guidance literature:: Multi-step reaction with 5 steps

1.1: 95 percent / Et₃N / CH₂Cl₂ / 0.5 h / 0 °C

2.1: 95 percent / HF-pyridine; pyridine / tetrahydrofuran / 12 h / 20 °C

3.1: Dess-Martin periodinane / CH₂Cl₂ / 0 - 20 °C

4.1: Mg; 1,2-dibromoethane / tetrahydrofuran / 1 h / 20 °C

4.2: 1.83 g / tetrahydrofuran / 10 h / 20 °C

5.1: 69 percent / trifllic acid / diethyl ether / 72 h / 20 °C

With pyridine; trifluorormethanesulfonic acid; Dess-Martin periodane; pyridine hydrogenfluoride; magnesium; ethylene dibromide; triethylamine; In tetrahydrofuran; diethyl ether; dichloromethane; 3.1: Dess-Martin oxidation / 4.2: Grignard reaction;
DOI:10.1016/S0968-0896(03)00186-X

Reference yield:

: 623926-29-4
(2R,3S,4S)-3-(tert-butyldimethylsilanyloxy)-2,4-dimethylhex-5-enal

: 623926-33-0
(4R,5S,6S,7S)-1,6-bis(tert-butyldimethylsilanyloxy)-5,7-dimethylnon-8-en-4-yl 4-methoxybenzyl ether

Guidance literature:: Multi-step reaction with 2 steps

1.1: Mg; 1,2-dibromoethane / tetrahydrofuran / 1 h / 20 °C

1.2: 1.83 g / tetrahydrofuran / 10 h / 20 °C

2.1: 69 percent / trifllic acid / diethyl ether / 72 h / 20 °C

With trifluorormethanesulfonic acid; magnesium; ethylene dibromide; In tetrahydrofuran; diethyl ether; 1.2: Grignard reaction;
DOI:10.1016/S0968-0896(03)00186-X