C₃₆H₄₇N₃O₉S

Base Information

• Chemical Name: C₃₆H₄₇N₃O₉S
• CAS No.: 1333120-83-4
• Molecular Formula: C₃₆H₄₇N₃O₉S
• Molecular Weight: 697.85
• Mol file: 1333120-83-4.mol

Synonyms:C₃₆H₄₇N₃O₉S

Chemical Property of C₃₆H₄₇N₃O₉S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₆H₄₇N₃O₉S

There total 9 articles about C₃₆H₄₇N₃O₉S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

C23H26N2O6S (1333120-78-7) + C19H22F5NO4 (1333120-82-3) → C36H47N3O9S (1333120-83-4)

Guidance literature:

C₂₃H₂₆N₂O₆S; With lithium hexamethyldisilazane; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane; at -78 ℃; Inert atmosphere;

C₁₉H₂₂F₅NO₄; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane; at -78 ℃; Inert atmosphere;

With acetic acid; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane; at -78 - 20 ℃; diastereoselective reaction; Inert atmosphere;

DOI:10.1021/ol2020362

Reference yield:

C14H27NO4 (1333120-91-4) → C36H47N3O9S (1333120-83-4)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium periodate; rhodium(III) chloride hydrate / water; acetonitrile / 16 h / 20 °C / Inert atmosphere

2.1: diisopropyl-carbodiimide / tetrahydrofuran / 6 h / 20 °C / Inert atmosphere

3.1: lithium hexamethyldisilazane / tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane / -78 °C / Inert atmosphere

3.2: -78 °C / Inert atmosphere

3.3: -78 - 20 °C / Inert atmosphere

With sodium periodate; rhodium(III) chloride hydrate; lithium hexamethyldisilazane; diisopropyl-carbodiimide; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane; water; acetonitrile;

DOI:10.1021/ol2020362

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) → C36H47N3O9S (1333120-83-4)

Guidance literature:

Multi-step reaction with 6 steps

1.1: (S)-Mandelic acid / methanol; diethyl ether / 48 h / 0 - 4 °C / Resolution of racemate; Inert atmosphere

1.2: 20 °C / Inert atmosphere

2.1: N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium / diethyl ether; cyclohexane / 7 h / -78 °C / Inert atmosphere

2.2: 1 h / -78 °C / Inert atmosphere

2.3: -78 - 20 °C / Inert atmosphere

3.1: 1,4-diaza-bicyclo[2.2.2]octane; osmium(VIII) oxide; potassium carbonate; potassium hexacyanoferrate(III) / water; tert-butyl alcohol / 20 °C / Inert atmosphere

4.1: sodium periodate; rhodium(III) chloride hydrate / water; acetonitrile / 16 h / 20 °C / Inert atmosphere

5.1: diisopropyl-carbodiimide / tetrahydrofuran / 6 h / 20 °C / Inert atmosphere

6.1: lithium hexamethyldisilazane / tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane / -78 °C / Inert atmosphere

6.2: -78 °C / Inert atmosphere

6.3: -78 - 20 °C / Inert atmosphere

With 1,4-diaza-bicyclo[2.2.2]octane; sodium periodate; osmium(VIII) oxide; N,N,N,N,-tetramethylethylenediamine; rhodium(III) chloride hydrate; (S)-Mandelic acid; sec.-butyllithium; potassium carbonate; lithium hexamethyldisilazane; potassium hexacyanoferrate(III); diisopropyl-carbodiimide; In tetrahydrofuran; methanol; N,N,N,N,N,N-hexamethylphosphoric triamide; diethyl ether; hexane; cyclohexane; water; acetonitrile; tert-butyl alcohol;

DOI:10.1021/ol2020362

upstream raw materials:

C₁₃H₂₃NO₄

C₂₃H₂₆N₂O₆S

C₁₉H₂₂F₅NO₄

C₁₄H₂₇NO₄

Downstream raw materials:

C₂₇H₂₉N₃O₆S

C₃₀H₃₅N₃O₆S

C₃₀H₃₅N₃O₆S