(2S,3S)-2-amino-N-{1,1-dimethyl-2-[methyl(phenyl)amino]-2-thioxoethyl}-3-methylpentanamide

Base Information

Chemical Name:(2S,3S)-2-amino-N-{1,1-dimethyl-2-[methyl(phenyl)amino]-2-thioxoethyl}-3-methylpentanamide
CAS No.:351196-93-5
Molecular Formula:C₁₇H₂₇N₃OS
Molecular Weight:321.487
Hs Code.:

Synonyms:(2S,3S)-2-amino-N-{1,1-dimethyl-2-[methyl(phenyl)amino]-2-thioxoethyl}-3-methylpentanamide

Suppliers and Price of (2S,3S)-2-amino-N-{1,1-dimethyl-2-[methyl(phenyl)amino]-2-thioxoethyl}-3-methylpentanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3S)-2-amino-N-{1,1-dimethyl-2-[methyl(phenyl)amino]-2-thioxoethyl}-3-methylpentanamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3S)-2-amino-N-{1,1-dimethyl-2-[methyl(phenyl)amino]-2-thioxoethyl}-3-methylpentanamide

There total 4 articles about (2S,3S)-2-amino-N-{1,1-dimethyl-2-[methyl(phenyl)amino]-2-thioxoethyl}-3-methylpentanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 238748-82-8
(9H-Fluoren-9-yl)methyl N-<(1S,2S)-2-methyl-1-<<<1,1-dimethyl-2--2-thioxoethyl>amino>carbonyl>butyl>carbamate

: 351196-93-5
(2S,3S)-2-amino-N-{1,1-dimethyl-2-[methyl(phenyl)amino]-2-thioxoethyl}-3-methylpentanamide

Guidance literature:: With diethylamine; In acetonitrile; at 25 ℃; for 21h;
DOI:10.1002/1522-2675(20010418)84:4<786::AID-HLCA786>3.0.CO;2-A

Reference yield:

: 238748-80-6
tert-butyl N-<(1S,2S)-2-methyl-1-<<<1,1-dimethyl-2--2-thioxoethyl>amino>carbonyl>butyl>carbamate

: 351196-93-5
(2S,3S)-2-amino-N-{1,1-dimethyl-2-[methyl(phenyl)amino]-2-thioxoethyl}-3-methylpentanamide

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; water; for 15h; Ambient temperature;
DOI:10.1002/(SICI)1522-2675(19990609)82:6<888::AID-HLCA888>3.0.CO;2-5

Reference yield:

: 13139-16-7
N-(tert-butyloxycarbonyl)-L-isoleucine

: 351196-93-5
(2S,3S)-2-amino-N-{1,1-dimethyl-2-[methyl(phenyl)amino]-2-thioxoethyl}-3-methylpentanamide

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) isobutyl chloroformate, N-methylmorpholine, 2.) H₂S / 1.) THF, -10 deg C, 5 min, 2.) THF, -10 deg C, 1 h

2: CH₂Cl₂ / 0.5 h / Ambient temperature

3: 3M HCl / tetrahydrofuran; H₂O / 15 h / Ambient temperature

With 4-methyl-morpholine; hydrogenchloride; hydrogen sulfide; isobutyl chloroformate; In tetrahydrofuran; dichloromethane; water;
DOI:10.1002/(SICI)1522-2675(19990609)82:6<888::AID-HLCA888>3.0.CO;2-5