(4-bromo-2-ethylphenoxy)triisopropylsilane

Base Information

• Chemical Name: (4-bromo-2-ethylphenoxy)triisopropylsilane
• CAS No.: 1016161-80-0
• Molecular Formula: C₁₇H₂₉BrOSi
• Molecular Weight: 357.406
• Mol file: 1016161-80-0.mol

Synonyms:(4-bromo-2-ethylphenoxy)triisopropylsilane

Chemical Property of (4-bromo-2-ethylphenoxy)triisopropylsilane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4-bromo-2-ethylphenoxy)triisopropylsilane

There total 1 articles about (4-bromo-2-ethylphenoxy)triisopropylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

triisopropylsilyl chloride (13154-24-0) + 4-bromo-2-ethylphenol (18980-21-7) → (4-bromo-2-ethylphenoxy)triisopropylsilane (1016161-80-0)

Guidance literature:

With sodium hydride; In tetrahydrofuran; mineral oil; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1016/j.ejmech.2016.08.003

Reference yield: 88.0%

(4-bromo-2-ethylphenoxy)triisopropylsilane (1016161-80-0) → C17H31BO3Si (1016161-84-4)

Guidance literature:

(4-bromo-2-ethylphenoxy)triisopropylsilane; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h;

With Triisopropyl borate; In tetrahydrofuran; hexane; at 20 ℃; for 1h;

With hydrogenchloride; In tetrahydrofuran; hexane; at 20 ℃; Further stages.;

DOI:10.1016/j.bmc.2007.10.040

Reference yield: 40.0%

(4-bromo-2-ethylphenoxy)triisopropylsilane (1016161-80-0) + trimethylsilylacetylene (1066-54-2) → (2-ethyl-4-((trimethylsilyl)ethynyl)phenoxy)triisopropylsilane

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; In acetonitrile; at 66 ℃; Inert atmosphere;

DOI:10.1016/j.ejmech.2016.08.003

upstream raw materials:

triisopropylsilyl chloride

4-bromo-2-ethylphenol

Downstream raw materials:

C₁₇H₃₁BO₃Si

Refernces

• 1、 Ocasio, Cory A.,Scanlan, Thomas S.. "Characterization of thyroid hormone receptor α (TRα)-specific analogs with varying inner- and outer-ring substituents". . p. 762 - 770. Retrieved 2008/09/17.