<1S-<1α,2α(Z),3α(E,3S^*,4R^*),4α>>-7-<3-(3-hydroxy-4-phenyl-1-pentenyl)-7-oxabicyclo<2.2.1>hept-2-yl>-4-heptenoic acid

Base Information

• Chemical Name: <1S-<1α,2α(Z),3α(E,3S^*,4R^*),4α>>-7-<3-(3-hydroxy-4-phenyl-1-pentenyl)-7-oxabicyclo<2.2.1>hept-2-yl>-4-heptenoic acid
• CAS No.: 126295-65-6
• Molecular Formula: C₂₄H₃₂O₄
• Molecular Weight: 384.516

Synonyms:<1S-<1α,2α(Z),3α(E,3S^*,4R^*),4α>>-7-<3-(3-hydroxy-4-phenyl-1-pentenyl)-7-oxabicyclo<2.2.1>hept-2-yl>-4-heptenoic acid

Chemical Property of <1S-<1α,2α(Z),3α(E,3S^*,4R^*),4α>>-7-<3-(3-hydroxy-4-phenyl-1-pentenyl)-7-oxabicyclo<2.2.1>hept-2-yl>-4-heptenoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of <1S-<1α,2α(Z),3α(E,3S^*,4R^*),4α>>-7-<3-(3-hydroxy-4-phenyl-1-pentenyl)-7-oxabicyclo<2.2.1>hept-2-yl>-4-heptenoic acid

There total 6 articles about <1S-<1α,2α(Z),3α(E,3S^*,4R^*),4α>>-7-<3-(3-hydroxy-4-phenyl-1-pentenyl)-7-oxabicyclo<2.2.1>hept-2-yl>-4-heptenoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(Z)-7-{(1S,2R,3S,4R)-3-[(E)-(3R,4S)-4-Phenyl-3-(tetrahydro-pyran-2-yloxy)-pent-1-enyl]-7-oxa-bicyclo[2.2.1]hept-2-yl}-hept-4-enoic acid → <1S-<1α,2α(Z),3α(E,3S*,4R*),4α>>-7-<3-(3-hydroxy-4-phenyl-1-pentenyl)-7-oxabicyclo<2.2.1>hept-2-yl>-4-heptenoic acid (126295-65-6)

Guidance literature:

With amberlyst-15 resin; In methanol; at 25 ℃; for 18h;

DOI:10.1021/jm00168a032

Reference yield:

1S-<1α,2α,3α(E,3S*,4R*),4α>-7-<3-<4-phenyl-3-(tetrahydropyranyloxy)-1-pentenyl>-7-oxabicyclo<2.2.1>hept-2-yl>acetaldehyde (126451-84-1) → <1S-<1α,2α(Z),3α(E,3S*,4R*),4α>>-7-<3-(3-hydroxy-4-phenyl-1-pentenyl)-7-oxabicyclo<2.2.1>hept-2-yl>-4-heptenoic acid (126295-65-6)

Guidance literature:

Multi-step reaction with 4 steps

1: 1.) potassium tert-amylate / 1a.) THF/toluenem, from 0 deg C to RT, 1b.) RT, 1 h, 2a.) from 0 deg C to RT, 2b.) RT, 1 h

2: 360 mg / 2 N aq. HCl / tetrahydrofuran / 2 h

3: 1.) potassium tert-amylate / 1.) THF/toluene, 0 deg C, 1h, 2.) 25 deg C, 1 h

4: Amberlyst-15 resin / methanol / 18 h / 25 °C

With hydrogenchloride; amberlyst-15 resin; potassium 2-methylbutan-2-olate; In tetrahydrofuran; methanol;

DOI:10.1021/jm00168a032

Reference yield:

(1S,2R,3S,4R)-2-((E)-3-Methoxy-allyl)-3-[(E)-(3R,4S)-4-phenyl-3-(tetrahydro-pyran-2-yloxy)-pent-1-enyl]-7-oxa-bicyclo[2.2.1]heptane (126295-71-4) → <1S-<1α,2α(Z),3α(E,3S*,4R*),4α>>-7-<3-(3-hydroxy-4-phenyl-1-pentenyl)-7-oxabicyclo<2.2.1>hept-2-yl>-4-heptenoic acid (126295-65-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 360 mg / 2 N aq. HCl / tetrahydrofuran / 2 h

2: 1.) potassium tert-amylate / 1.) THF/toluene, 0 deg C, 1h, 2.) 25 deg C, 1 h

3: Amberlyst-15 resin / methanol / 18 h / 25 °C

With hydrogenchloride; amberlyst-15 resin; potassium 2-methylbutan-2-olate; In tetrahydrofuran; methanol;

DOI:10.1021/jm00168a032

upstream raw materials:

1S-<1α,2α,3α(E,3S^*,4R^*),4α>-7-<3-<4-phenyl-3-(tetrahydropyranyloxy)-1-pentenyl>-7-oxabicyclo<2.2.1>hept-2-yl>acetaldehyde

3-{(1S,2R,3S,4R)-3-[(E)-(3R,4S)-4-Phenyl-3-(tetrahydro-pyran-2-yloxy)-pent-1-enyl]-7-oxa-bicyclo[2.2.1]hept-2-yl}-propionaldehyde

(1S,2R,3S,4R)-2-((E)-3-Methoxy-allyl)-3-[(E)-(3R,4S)-4-phenyl-3-(tetrahydro-pyran-2-yloxy)-pent-1-enyl]-7-oxa-bicyclo[2.2.1]heptane

5,6-Dihydroxy-7-{(1S,2R,3S,4R)-3-[(E)-(3R,4S)-4-phenyl-3-(tetrahydro-pyran-2-yloxy)-pent-1-enyl]-7-oxa-bicyclo[2.2.1]hept-2-yl}-heptanoic acid methyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 126295-65-6 <1S-<1α,2α(Z),3α(E,3S^*,4R^*),4α>>-7-<3-(3-hydroxy-4-phenyl-1-pentenyl)-7-oxabicyclo<2.2.1>hept-2-yl>-4-heptenoic acid

Send

Send

Metric Ton KG G Pound L ML

Send

Send