(4-chlorophenyl)carbamic acid (S)-2,2,2-trifluoro-1-[3-(3-methyl-[1,2,4]oxadiazol-5-yl)-piperidin-1-ylmethyl]-ethyl ester hydrochloride

Base Information

Chemical Name:(4-chlorophenyl)carbamic acid (S)-2,2,2-trifluoro-1-[3-(3-methyl-[1,2,4]oxadiazol-5-yl)-piperidin-1-ylmethyl]-ethyl ester hydrochloride
CAS No.:1602922-99-5
Molecular Formula:C₁₈H₂₀ClF₃N₄O₃*ClH
Molecular Weight:469.291
Hs Code.:

Synonyms:(4-chlorophenyl)carbamic acid (S)-2,2,2-trifluoro-1-[3-(3-methyl-[1,2,4]oxadiazol-5-yl)-piperidin-1-ylmethyl]-ethyl ester hydrochloride

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Chemical Property of (4-chlorophenyl)carbamic acid (S)-2,2,2-trifluoro-1-[3-(3-methyl-[1,2,4]oxadiazol-5-yl)-piperidin-1-ylmethyl]-ethyl ester hydrochloride

Chemical Property:

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Technology Process of (4-chlorophenyl)carbamic acid (S)-2,2,2-trifluoro-1-[3-(3-methyl-[1,2,4]oxadiazol-5-yl)-piperidin-1-ylmethyl]-ethyl ester hydrochloride

There total 3 articles about (4-chlorophenyl)carbamic acid (S)-2,2,2-trifluoro-1-[3-(3-methyl-[1,2,4]oxadiazol-5-yl)-piperidin-1-ylmethyl]-ethyl ester hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1603165-03-2
(4-chlorophenyl)carbamic acid (S)-2,2,2-trifluoro-1-[3-(3-methyl-[1,2,4]oxadiazol-5-yl)-piperidin-1-ylmethyl]-ethyl ester

: 1602922-99-5
(4-chlorophenyl)carbamic acid (S)-2,2,2-trifluoro-1-[3-(3-methyl-[1,2,4]oxadiazol-5-yl)-piperidin-1-ylmethyl]-ethyl ester hydrochloride

Guidance literature:: With hydrogenchloride; In diethyl ether; Inert atmosphere;

Reference yield:

: 1602924-02-6
(S)-1,1,1-trifluoro-3-[3-(3-methyl-[1,2,4]oxadiazol-5yl)-piperidin-1-yl]-propan-2-ol

: 1602922-99-5
(4-chlorophenyl)carbamic acid (S)-2,2,2-trifluoro-1-[3-(3-methyl-[1,2,4]oxadiazol-5-yl)-piperidin-1-ylmethyl]-ethyl ester hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: acetonitrile / 3 h / 85 °C / Inert atmosphere

2: hydrogenchloride / diethyl ether / Inert atmosphere

With hydrogenchloride; In diethyl ether; acetonitrile;

Reference yield:

: 902837-17-6
3-methyl-5-(piperidin-3-yl)-1,2,4-oxadiazole

: 1602922-99-5
(4-chlorophenyl)carbamic acid (S)-2,2,2-trifluoro-1-[3-(3-methyl-[1,2,4]oxadiazol-5-yl)-piperidin-1-ylmethyl]-ethyl ester hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: N-ethyl-N,N-diisopropylamine / dichloromethane / 3 h / 20 °C / Inert atmosphere

2: acetonitrile / 3 h / 85 °C / Inert atmosphere

3: hydrogenchloride / diethyl ether / Inert atmosphere

With hydrogenchloride; N-ethyl-N,N-diisopropylamine; In diethyl ether; dichloromethane; acetonitrile;