Technology Process of 13-hydroxypodocarpa-6,8,11,13-tetraene
There total 2 articles about 13-hydroxypodocarpa-6,8,11,13-tetraene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: potassium permanganate; phenyltrimethylammonium chloride / chloroform / 24 h / 10 °C
2: ozone / dichloromethane / 0.25 h
3: sulfuric acid / methanol / 2 h / Reflux
4: acetic acid / benzene / 48 h / 80 °C
5: lithium bromide; copper(ll) bromide / acetonitrile / 0.5 h / 20 °C
With
potassium permanganate; sulfuric acid; phenyltrimethylammonium chloride; ozone; acetic acid; lithium bromide; copper(ll) bromide;
In
methanol; dichloromethane; chloroform; acetonitrile; benzene;
3: Aldol condensation;
DOI:10.1080/00397911.2010.492078
- Guidance literature:
-
Multi-step reaction with 4 steps
1: potassium permanganate; phenyltrimethylammonium chloride / chloroform / 24 h / 10 °C
2: ozone / dichloromethane / 0.25 h
3: sulfuric acid / methanol / 2 h / Reflux
4: lithium bromide; copper(ll) bromide / acetonitrile / 0.17 h / 20 °C
With
potassium permanganate; sulfuric acid; phenyltrimethylammonium chloride; ozone; lithium bromide; copper(ll) bromide;
In
methanol; dichloromethane; chloroform; acetonitrile;
3: Aldol condensation;
DOI:10.1080/00397911.2010.492078
