2-ethyl-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin-6-yl 2,4-dinitrobenzenesulfonate

Base Information

• Chemical Name: 2-ethyl-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin-6-yl 2,4-dinitrobenzenesulfonate
• CAS No.: 1384524-85-9
• Molecular Formula: C₂₀H₁₃N₃O₉S
• Molecular Weight: 471.404
• Mol file: 1384524-85-9.mol

Synonyms:2-ethyl-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin-6-yl 2,4-dinitrobenzenesulfonate

Chemical Property of 2-ethyl-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin-6-yl 2,4-dinitrobenzenesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-ethyl-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin-6-yl 2,4-dinitrobenzenesulfonate

There total 2 articles about 2-ethyl-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin-6-yl 2,4-dinitrobenzenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.9%

2,4-dinitrobenzenesulfonyl chloride (1656-44-6) + 2-ethyl-6-hydroxy-1H-benzo[de]isoquinoline-1,3(2H)-dione (42359-42-2) → 2-ethyl-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin-6-yl 2,4-dinitrobenzenesulfonate (1384524-85-9)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 4h;

DOI:10.1016/j.tet.2012.04.110

Reference yield:

6-bromo-2-ethyl-1H-benzo[de]isoquinoline-1,3(2H)dione (100874-09-7) → 2-ethyl-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin-6-yl 2,4-dinitrobenzenesulfonate (1384524-85-9)

Guidance literature:

Multi-step reaction with 3 steps

1: copper(ll) sulfate pentahydrate / methanol / 12 h / Reflux

2: hydrogen iodide / 6 h / Reflux

3: triethylamine / dichloromethane / 4 h / 0 - 20 °C

With copper(ll) sulfate pentahydrate; hydrogen iodide; triethylamine; In methanol; dichloromethane;

DOI:10.1016/j.tet.2012.04.110

upstream raw materials:

2,4-dinitrobenzenesulfonyl chloride

2-ethyl-6-hydroxy-1H-benzo[de]isoquinoline-1,3(2H)-dione

6-bromo-2-ethyl-1H-benzo[de]isoquinoline-1,3(2H)dione