4-[(3-amino-5-cyanophenyl)amino]-7-chloro-1-[2-(piperidin-1-yl)ethyl]quinolin-1-ium chloride

Base Information

Chemical Name:4-[(3-amino-5-cyanophenyl)amino]-7-chloro-1-[2-(piperidin-1-yl)ethyl]quinolin-1-ium chloride
CAS No.:1312291-14-7
Molecular Formula:C₂₃H₂₅ClN₅*Cl
Molecular Weight:442.391
Hs Code.:

Synonyms:4-[(3-amino-5-cyanophenyl)amino]-7-chloro-1-[2-(piperidin-1-yl)ethyl]quinolin-1-ium chloride

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Chemical Property of 4-[(3-amino-5-cyanophenyl)amino]-7-chloro-1-[2-(piperidin-1-yl)ethyl]quinolin-1-ium chloride

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Technology Process of 4-[(3-amino-5-cyanophenyl)amino]-7-chloro-1-[2-(piperidin-1-yl)ethyl]quinolin-1-ium chloride

There total 3 articles about 4-[(3-amino-5-cyanophenyl)amino]-7-chloro-1-[2-(piperidin-1-yl)ethyl]quinolin-1-ium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

: 1312291-13-6
3-amino-5-[(7-chloroquinolin-4-yl)amino]benzonitrile hydrochloride

: 2008-75-5
N-chloroethylpiperidine hydrochloride

: 1312291-14-7
4-[(3-amino-5-cyanophenyl)amino]-7-chloro-1-[2-(piperidin-1-yl)ethyl]quinolin-1-ium chloride

Guidance literature:: With potassium carbonate; In acetonitrile; for 48h; Reflux;

Reference yield:

: 4110-35-4
3,5-dinitrobenzonitrile

: 1312291-14-7
4-[(3-amino-5-cyanophenyl)amino]-7-chloro-1-[2-(piperidin-1-yl)ethyl]quinolin-1-ium chloride

Guidance literature:: Multi-step reaction with 3 steps

1.1: hydrogenchloride; tin(ll) chloride / water / 2 h / 20 °C

1.2: 0 °C

2.1: ethanol / 18 h / 20 °C

3.1: potassium carbonate / acetonitrile / 48 h / Reflux

With hydrogenchloride; potassium carbonate; tin(ll) chloride; In ethanol; water; acetonitrile;

Reference yield:

: 33786-93-5
3,5-diaminobenzonitrile

: 1312291-14-7
4-[(3-amino-5-cyanophenyl)amino]-7-chloro-1-[2-(piperidin-1-yl)ethyl]quinolin-1-ium chloride

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol / 18 h / 20 °C

2: potassium carbonate / acetonitrile / 48 h / Reflux

With potassium carbonate; In ethanol; acetonitrile;