C₆₆H₉₇NO₈S

Base Information

• Chemical Name: C₆₆H₉₇NO₈S
• CAS No.: 1431220-33-5
• Molecular Formula: C₆₆H₉₇NO₈S
• Molecular Weight: 1064.56
• Mol file: 1431220-33-5.mol

Synonyms:C₆₆H₉₇NO₈S

Chemical Property of C₆₆H₉₇NO₈S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₆₆H₉₇NO₈S

There total 16 articles about C₆₆H₉₇NO₈S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C48H71NO7S + 12-Phenyldodecanoic Acid (14507-27-8) → C66H97NO8S (1431220-33-5)

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃;

DOI:10.3998/ark.5550190.0014.224

Reference yield:

tetradecylmagnesium bromide (88303-25-7) → C66H97NO8S (1431220-33-5)

Guidance literature:

Multi-step reaction with 10 steps

1.1: tetrahydrofuran

2.1: pyridine

3.1: toluene-4-sulfonic acid / methanol; dichloromethane

4.1: sodium azide / N,N-dimethyl-formamide / Heating

5.1: toluene-4-sulfonic acid

6.1: pyridine

7.1: lithium iodide / N,N-dimethyl-formamide

8.1: sodium hydrogencarbonate; tetra(n-butyl)ammonium hydrogensulfate / ethyl acetate

9.1: triphenylphosphine / tetrahydrofuran / 2 h / 20 °C

9.2: Staudinger Azide Reduction / 2 h

10.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 20 °C

With pyridine; sodium azide; tetra(n-butyl)ammonium hydrogensulfate; sodium hydrogencarbonate; toluene-4-sulfonic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triphenylphosphine; lithium iodide; In tetrahydrofuran; methanol; dichloromethane; ethyl acetate; N,N-dimethyl-formamide; 1.1: |Grignard Reaction / 9.1: |Staudinger Azide Reduction;

DOI:10.3998/ark.5550190.0014.224

Reference yield:

(2R,3R,4R)-1,3,4-trihydroxyoctadecan-2-yl methanesulfonate (160280-65-9) → C66H97NO8S (1431220-33-5)

Guidance literature:

Multi-step reaction with 7 steps

1.1: sodium azide / N,N-dimethyl-formamide / Heating

2.1: toluene-4-sulfonic acid

3.1: pyridine

4.1: lithium iodide / N,N-dimethyl-formamide

5.1: sodium hydrogencarbonate; tetra(n-butyl)ammonium hydrogensulfate / ethyl acetate

6.1: triphenylphosphine / tetrahydrofuran / 2 h / 20 °C

6.2: Staudinger Azide Reduction / 2 h

7.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 20 °C

With pyridine; sodium azide; tetra(n-butyl)ammonium hydrogensulfate; sodium hydrogencarbonate; toluene-4-sulfonic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triphenylphosphine; lithium iodide; In tetrahydrofuran; dichloromethane; ethyl acetate; N,N-dimethyl-formamide; 6.1: |Staudinger Azide Reduction;

DOI:10.3998/ark.5550190.0014.224

upstream raw materials:

(2R,3R,4R)-1,3,4-trihydroxyoctadecan-2-yl methanesulfonate

(2S,3S,4R)-2-azido-1,3,4-octadecanetriol

(2S,3S,4R)-2-aminooctadecane-1,3,4-triol hydrochloride

C₂₅H₄₉N₃O₄

Downstream raw materials:

C₆₃H₉₃NO₈S

C₄₂H₇₅NO₈S

Refernces