[1092]2-[(Furan-2-ylmethyl)-amino]-4-(4-methyl-piperazin-1-yl)-benzoic acid methyl ester

Base Information

• Chemical Name: [1092]2-[(Furan-2-ylmethyl)-amino]-4-(4-methyl-piperazin-1-yl)-benzoic acid methyl ester
• CAS No.: 897027-11-1
• Molecular Formula: C₁₈H₂₃N₃O₃
• Molecular Weight: 329.399

Synonyms:[1092]2-[(Furan-2-ylmethyl)-amino]-4-(4-methyl-piperazin-1-yl)-benzoic acid methyl ester

Chemical Property of [1092]2-[(Furan-2-ylmethyl)-amino]-4-(4-methyl-piperazin-1-yl)-benzoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [1092]2-[(Furan-2-ylmethyl)-amino]-4-(4-methyl-piperazin-1-yl)-benzoic acid methyl ester

There total 2 articles about [1092]2-[(Furan-2-ylmethyl)-amino]-4-(4-methyl-piperazin-1-yl)-benzoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 21.0%

2-chloro-4-(4-methylpiperazin-1-yl)benzoic acid methyl ester (1059705-62-2) + furan-2-ylmethanamine (617-89-0) + sodium tert-pentoxide (14593-46-5) → [1092]2-[(Furan-2-ylmethyl)-amino]-4-(4-methyl-piperazin-1-yl)-benzoic acid methyl ester (897027-11-1) + tert-pentyl 2-((furan-2-ylmethyl)amino)-4-(4-methylpiperazin-1-yl)benzoate (1059705-64-4)

Guidance literature:

With 2-P(t-Bu)2-biphenyl; tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; In toluene; at 110 ℃; for 20h;

DOI:10.1002/adsc.200700133

Reference yield: 9.0%

2-chloro-4-(4-methylpiperazin-1-yl)benzoic acid methyl ester (1059705-62-2) + furan-2-ylmethanamine (617-89-0) → [1092]2-[(Furan-2-ylmethyl)-amino]-4-(4-methyl-piperazin-1-yl)-benzoic acid methyl ester (897027-11-1)

Guidance literature:

With potassium phosphate; palladium diacetate; In 1,2-dimethoxyethane; at 100 ℃; for 20h;

DOI:10.1002/adsc.200700133

Reference yield:

[1092]2-[(Furan-2-ylmethyl)-amino]-4-(4-methyl-piperazin-1-yl)-benzoic acid methyl ester (897027-11-1) → 2-[(Furan-2-ylmethyl)-amino]-4-(4-methyl-piperazin-1-yl)-benzoic acid

Guidance literature:

With lithium hydroxide; In 1,4-dioxane; at 20 ℃; for 20h;

DOI:10.1016/j.bmcl.2007.09.016

upstream raw materials:

2-chloro-4-(4-methylpiperazin-1-yl)benzoic acid methyl ester

furan-2-ylmethanamine

sodium tert-pentoxide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 897027-11-1 [1092]2-[(Furan-2-ylmethyl)-amino]-4-(4-methyl-piperazin-1-yl)-benzoic acid methyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send