Technology Process of C22H32O5S
There total 1 articles about C22H32O5S which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
1-methyl-1H-imidazole; triethylamine; lithium chloride;
In
toluene;
at 0 - 20 ℃;
for 27h;
optical yield given as %de;
diastereoselective reaction;
Inert atmosphere;
DOI:10.1016/j.tet.2011.10.080
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: bis-triphenylphosphine-palladium(II) chloride / tetrahydrofuran / 0.75 h / 0 - 20 °C / Inert atmosphere
2.1: diisobutylaluminium hydride / hexane; toluene / 0.17 h / -78 °C / Inert atmosphere
2.2: -78 °C
3.1: titanium(IV) isopropylate; tert.-butylhydroperoxide; L-(+)-diisopropyl tartrate / dichloromethane / 2 h / -50 °C / Molecular sieve
4.1: dmap; triethylamine / dichloromethane / 4 h / 0 °C
With
titanium(IV) isopropylate; tert.-butylhydroperoxide; dmap; bis-triphenylphosphine-palladium(II) chloride; L-(+)-diisopropyl tartrate; diisobutylaluminium hydride; triethylamine;
In
tetrahydrofuran; hexane; dichloromethane; toluene;
1.1: Negishi coupling reaction / 3.1: Sharpless-Katsuki epoxidation;
DOI:10.1016/j.tet.2011.10.080
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: bis-triphenylphosphine-palladium(II) chloride / tetrahydrofuran / 0.75 h / 0 - 20 °C / Inert atmosphere
2.1: diisobutylaluminium hydride / hexane; toluene / 0.17 h / -78 °C / Inert atmosphere
2.2: -78 °C
3.1: titanium(IV) isopropylate; tert.-butylhydroperoxide; L-(+)-diisopropyl tartrate / dichloromethane / 2 h / -50 °C / Molecular sieve
4.1: sulfur trioxide pyridine complex; dimethyl sulfoxide; N-ethyl-N,N-diisopropylamine / dichloromethane / 1.5 h / 0 °C
5.1: sodium chlorite; sodium dihydrogenphosphate dihydrate; 2-methyl-but-2-ene / water; tert-butyl alcohol / 1.5 h / 0 - 20 °C
With
titanium(IV) isopropylate; tert.-butylhydroperoxide; bis-triphenylphosphine-palladium(II) chloride; sodium chlorite; sodium dihydrogenphosphate dihydrate; 2-methyl-but-2-ene; L-(+)-diisopropyl tartrate; sulfur trioxide pyridine complex; diisobutylaluminium hydride; dimethyl sulfoxide; N-ethyl-N,N-diisopropylamine;
In
tetrahydrofuran; hexane; dichloromethane; water; toluene; tert-butyl alcohol;
1.1: Negishi coupling reaction / 3.1: Sharpless-Katsuki epoxidation;
DOI:10.1016/j.tet.2011.10.080
