(5-methoxy-1H-indol-2-yl)-phenylmethanone

Base Information

Chemical Name:(5-methoxy-1H-indol-2-yl)-phenylmethanone
CAS No.:74588-78-6
Molecular Formula:C16H13 N O2
Molecular Weight:251.285
Hs Code.:
DSSTox Substance ID:DTXSID30397970
Nikkaji Number:J1.679.707C
Wikidata:Q27164211
Pharos Ligand ID:SHAS8U8Z8GDG
ChEMBL ID:CHEMBL140220
Mol file:74588-78-6.mol

Synonyms:5-methoxy-1H-2-indolyl-phenylmethanone;5-methoxy-1H-2-indolylphenylmethanone;D-64131;D64131

Suppliers and Price of (5-methoxy-1H-indol-2-yl)-phenylmethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
D-64131
10mg
$ 423.00

TRC
D-64131
250mg
$ 1260.00

Tocris
D-64131 ≥99%(HPLC)
10
$ 119.00

Tocris
D-64131 ≥99%(HPLC)
50
$ 497.00

DC Chemicals
D-64131 >98%
100 mg
$ 450.00

Crysdot
D-64131 98+%
50mg
$ 366.00

ChemScene
D-64131 99.17%
100mg
$ 550.00

ChemScene
D-64131 99.17%
50mg
$ 350.00

ChemScene
D-64131 99.17%
10mg
$ 88.00

Chemenu
(5-methoxy-1H-indol-2-yl)(phenyl)methanone 95%+
50mg
$ 235.00

Total 20 raw suppliers

Chemical Property of (5-methoxy-1H-indol-2-yl)-phenylmethanone

Chemical Property:

Vapor Pressure:1.79E-08mmHg at 25°C
Melting Point:162 °C
Refractive Index:1.656
Boiling Point:455.2°C at 760 mmHg
PKA:14.81±0.30(Predicted)
Flash Point:229.1°C
PSA：42.09000
Density:1.231g/cm³
LogP:3.40750
Storage Temp.:Store at RT
Solubility.:Soluble in DMSO
XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:251.094628657
Heavy Atom Count:19
Complexity:325

Purity/Quality:

99%, ^*data from raw suppliers

D-64131 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)NC(=C2)C(=O)C3=CC=CC=C3
Uses Novel inhibitor of tubulin polymerization

Technology Process of (5-methoxy-1H-indol-2-yl)-phenylmethanone

There total 27 articles about (5-methoxy-1H-indol-2-yl)-phenylmethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 370580-32-8
(5-methoxy-1-phenylsulfonyl-1H-2-indolyl)-phenylmethanone

: 74588-78-6
D-64131

Guidance literature:: With aq. 10percent NaOH; In ethanol; for 12h; Heating;
DOI:10.1021/jm010940+

Reference yield: 88.0%

: 74588-83-3
5-methoxy-2-benzoylindolyl-3-carboxylic acid

: 74588-78-6
D-64131

Guidance literature:: at 220 - 230 ℃; for 0.2h;
DOI:10.1007/BF00515352

Reference yield: 87.0%

: 1252576-12-7
N-(2-(chloromethyl)-4-methoxyphenyl)-4-methylbenzenesulfonamide

: 5633-34-1
(benzoylmethylene)dimethylsulfurane

: 74588-78-6
D-64131

Guidance literature:: (benzoylmethylene)dimethylsulfurane; With caesium carbonate; In 5,5-dimethyl-1,3-cyclohexadiene; at 20 ℃; for 0.5h;

C₁₅H₁₆ClNO₃S; In 5,5-dimethyl-1,3-cyclohexadiene; at 20 ℃;
DOI:10.1002/anie.201203657