2-[3-(aminomethyl)phenyl]-N,8-dimethyl-8H-imidazo[4,5-d]-thiazolo[5,4-b]pyridine-5-amine

Base Information

Chemical Name:2-[3-(aminomethyl)phenyl]-N,8-dimethyl-8H-imidazo[4,5-d]-thiazolo[5,4-b]pyridine-5-amine
CAS No.:805322-20-7
Molecular Formula:C₁₆H₁₆N₆S
Molecular Weight:324.409
Hs Code.:

Synonyms:2-[3-(aminomethyl)phenyl]-N,8-dimethyl-8H-imidazo[4,5-d]-thiazolo[5,4-b]pyridine-5-amine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-[3-(aminomethyl)phenyl]-N,8-dimethyl-8H-imidazo[4,5-d]-thiazolo[5,4-b]pyridine-5-amine

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Technology Process of 2-[3-(aminomethyl)phenyl]-N,8-dimethyl-8H-imidazo[4,5-d]-thiazolo[5,4-b]pyridine-5-amine

There total 2 articles about 2-[3-(aminomethyl)phenyl]-N,8-dimethyl-8H-imidazo[4,5-d]-thiazolo[5,4-b]pyridine-5-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 805322-17-2
3-[8-methyl-5-(methylamino)-8H-imidazo[4,5-d]thiazolo[5,4-b]pyridin-2-yl]-benzonitrile

: 805322-20-7
2-[3-(aminomethyl)phenyl]-N,8-dimethyl-8H-imidazo[4,5-d]-thiazolo[5,4-b]pyridine-5-amine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃;

Reference yield:

: 1134816-48-0
N-[[3-[8-methyl-5-methylamino-8H-imidazo[4,5-d]thiazolo[5,4-b]-pyridine-2-yl]phenyl]methyl]-tert-butyl carbamate

: 805322-20-7
2-[3-(aminomethyl)phenyl]-N,8-dimethyl-8H-imidazo[4,5-d]-thiazolo[5,4-b]pyridine-5-amine

Guidance literature:: With hydrogenchloride; water; In 1,4-dioxane; at 20 ℃; for 0.333333h; Inert atmosphere;
DOI:10.1021/jm8015816

Reference yield: 12.0%

: 805322-20-7
2-[3-(aminomethyl)phenyl]-N,8-dimethyl-8H-imidazo[4,5-d]-thiazolo[5,4-b]pyridine-5-amine

: 64-19-7,77671-22-8
acetic acid

: N-[[3-[8-methyl-5-(methylamino)-8H-imidazo[4,5-d]thiazolo[5,4-b]-pyridine-2-yl]phenyl]methyl]acetamide

Guidance literature:: With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 1h; Inert atmosphere;
DOI:10.1021/jm8015816