1-(n-butyl)-3-methyl-4-diphenylphosphinoimidazole-2-thione

Base Information

• Chemical Name: 1-(n-butyl)-3-methyl-4-diphenylphosphinoimidazole-2-thione
• CAS No.: 1372549-36-4
• Molecular Formula: C₂₀H₂₃N₂PS
• Molecular Weight: 354.456
• Mol file: 1372549-36-4.mol

Synonyms:1-(n-butyl)-3-methyl-4-diphenylphosphinoimidazole-2-thione

Chemical Property of 1-(n-butyl)-3-methyl-4-diphenylphosphinoimidazole-2-thione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 1-(n-butyl)-3-methyl-4-diphenylphosphinoimidazole-2-thione

There total 2 articles about 1-(n-butyl)-3-methyl-4-diphenylphosphinoimidazole-2-thione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

chloro-diphenylphosphine (1079-66-9,74391-44-9) + 1-butyl-3-methyl-1H-imidazole-2(3H)-thione (119393-94-1) → 1-(n-butyl)-3-methyl-4-diphenylphosphinoimidazole-2-thione (1372549-36-4) + 1-(n-butyl)-3-methyl-5-diphenylphosphinoimidazole-2-thione (1372549-40-0)

Guidance literature:

1-butyl-3-methyl-1H-imidazole-2(3H)-thione; With n-butyllithium; In tetrahydrofuran; hexane; at -80 - -40 ℃; Inert atmosphere;

chloro-diphenylphosphine; In tetrahydrofuran; hexane; at -80 - 20 ℃; Inert atmosphere;

DOI:10.1039/c2dt12483a

Reference yield:

1-methyl-3-(n-butyl)imidazolium iodide (65039-05-6) → 1-(n-butyl)-3-methyl-4-diphenylphosphinoimidazole-2-thione (1372549-36-4) + 1-(n-butyl)-3-methyl-5-diphenylphosphinoimidazole-2-thione (1372549-40-0)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sulfur / tetrahydrofuran / 2 h / 20 °C / Inert atmosphere

1.2: Inert atmosphere; Cooling

2.1: n-butyllithium / tetrahydrofuran; hexane / -80 - -40 °C / Inert atmosphere

2.2: -80 - 20 °C / Inert atmosphere

With sulfur; n-butyllithium; In tetrahydrofuran; hexane;

DOI:10.1039/c2dt12483a

Reference yield:

1-(n-butyl)-3-methyl-4-diphenylphosphinoimidazole-2-thione (1372549-36-4) → C20H23N2PS2

Guidance literature:

With sulfur; Schlenk technique; Inert atmosphere;

DOI:10.1039/c3dt51557e

upstream raw materials:

chloro-diphenylphosphine

1-butyl-3-methyl-1H-imidazole-2(3H)-thione

1-methyl-3-(n-butyl)imidazolium iodide