Technology Process of 1-benzylisoquinoline hydrochloride
There total 5 articles about 1-benzylisoquinoline hydrochloride which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride; sodium hydroxide;
In
ethanol; dichloromethane;
for 0.666667h;
Irradiation;
ultrasound sonication;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 69 percent / triethylbenzylammonmium chloride / CH2Cl2; H2O / 0.33 h / Irradiation; ultrasound sonication
2: 1.) 50percent aq. NaOH; 2.) 50percent aq. NaOH; HCl(g) / triethylbenzylammonium chloride / 1.) dichloromethane, 20 min, ultrasound sonication; 2.) dichloromethane, ethanol, 30 min, ultrasound sonication
With
hydrogenchloride; sodium hydroxide;
N-benzyl-N,N,N-triethylammonium chloride;
In
dichloromethane; water;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 60 percent / 50percent aq. NaOH / tetrabutylammonium chloride / CH2Cl2 / 0.33 h / Ambient temperature; ultrasound sonication
2: 70 percent / 1.) 50percent aq. NaOH; 2.) HCl(g) / CH2Cl2; ethanol / 0.67 h / Irradiation; ultrasound sonication
With
hydrogenchloride; sodium hydroxide;
tetrabutyl-ammonium chloride;
In
ethanol; dichloromethane;
