(5-cyano-2-nitro-phenyl)-(5-morpholin-4-ylmethyl-pyridin-2-yl)-acetic acid ethyl ester hydrochloride

Base Information

Chemical Name:(5-cyano-2-nitro-phenyl)-(5-morpholin-4-ylmethyl-pyridin-2-yl)-acetic acid ethyl ester hydrochloride
CAS No.:1073614-07-9
Molecular Formula:C₂₁H₂₂N₄O₅*ClH
Molecular Weight:446.89
Hs Code.:

Synonyms:(5-cyano-2-nitro-phenyl)-(5-morpholin-4-ylmethyl-pyridin-2-yl)-acetic acid ethyl ester hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (5-cyano-2-nitro-phenyl)-(5-morpholin-4-ylmethyl-pyridin-2-yl)-acetic acid ethyl ester hydrochloride

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Technology Process of (5-cyano-2-nitro-phenyl)-(5-morpholin-4-ylmethyl-pyridin-2-yl)-acetic acid ethyl ester hydrochloride

There total 1 articles about (5-cyano-2-nitro-phenyl)-(5-morpholin-4-ylmethyl-pyridin-2-yl)-acetic acid ethyl ester hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1073614-08-0
(5-cyano-2-nitro-phenyl)-(5-morpholin-4-ylmethyl-pyridin-2-yl)-acetic acid ethyl ester

: 1073614-07-9
(5-cyano-2-nitro-phenyl)-(5-morpholin-4-ylmethyl-pyridin-2-yl)-acetic acid ethyl ester hydrochloride

Guidance literature:: With hydrogenchloride; In ethanol; isopropyl alcohol; toluene; at -10 - 60 ℃; for 10h; Product distribution / selectivity;

Reference yield:

: 1073614-07-9
(5-cyano-2-nitro-phenyl)-(5-morpholin-4-ylmethyl-pyridin-2-yl)-acetic acid ethyl ester hydrochloride

: 1073614-09-1
(2-amino-5-cyano-phenyl)-(5-morpholin-4-ylmethyl-pyridin-2-yl)-acetic acid ethyl ester

Guidance literature:: (5-cyano-2-nitro-phenyl)-(5-morpholin-4-ylmethyl-pyridin-2-yl)-acetic acid ethyl ester hydrochloride; With sodium hydrogencarbonate; In water; toluene; at 20 ℃; for 0.75h;

With hydrogen; 3%Pt/0.6%V/C; In N,N-dimethyl-formamide; at 40 - 70 ℃; for 6.5h; under 2250.23 - 3000.3 Torr; Product distribution / selectivity;