N,N-dimethyl-4-oxo-5-phenylpentaneamide

Base Information

• Chemical Name: N,N-dimethyl-4-oxo-5-phenylpentaneamide
• CAS No.: 122715-97-3
• Molecular Formula: C₁₃H₁₇NO₂
• Molecular Weight: 219.283
• Mol file: 122715-97-3.mol

Synonyms:N,N-dimethyl-4-oxo-5-phenylpentaneamide

Chemical Property of N,N-dimethyl-4-oxo-5-phenylpentaneamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N-dimethyl-4-oxo-5-phenylpentaneamide

There total 6 articles about N,N-dimethyl-4-oxo-5-phenylpentaneamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

4-hydroxy-N,N-dimethyl-5-phenylpentanamide (924893-87-8) → N,N-dimethyl-4-oxo-5-phenylpentaneamide (122715-97-3)

Guidance literature:

With sodium bromate; ammonium cerium (IV) nitrate; In water; acetonitrile; for 0.75h; Reflux;

DOI:10.1002/ejoc.201101800

Reference yield: 69.0%

benzylmagnesium chloride (6921-34-2) → N,N-dimethyl-4-oxo-5-phenylpentaneamide (122715-97-3)

Guidance literature:

With t-butyl bromide; In diethyl ether; 1) -78 grad C, 1.5 h, 2) -78 grad C then to room temperature;

DOI:10.1016/S0040-4039(00)99673-4

Reference yield:

allylbenzene (300-57-2,57807-91-7) → N,N-dimethyl-4-oxo-5-phenylpentaneamide (122715-97-3)

Guidance literature:

Multi-step reaction with 3 steps

1.1: manganese triacetate

2.1: ethanol / 24 h / 20 °C

2.2: pH 1 - 2

3.1: ammonium cerium (IV) nitrate; sodium bromate / water; acetonitrile / 0.75 h / Reflux

With sodium bromate; ammonium cerium (IV) nitrate; manganese triacetate; In ethanol; water; acetonitrile;

DOI:10.1002/ejoc.201101800

upstream raw materials:

benzylmagnesium chloride

4-hydroxy-N,N-dimethyl-5-phenylpentanamide

allylbenzene

(±)-5-benzyldihydrofuran-2(3H)-one