[1-Amino-1-phenethylamino-meth-(Z)-ylidene]-sulfamic acid 2,2,2-trichloro-ethyl ester

Base Information

• Chemical Name: [1-Amino-1-phenethylamino-meth-(Z)-ylidene]-sulfamic acid 2,2,2-trichloro-ethyl ester
• CAS No.: 882739-51-7
• Molecular Formula: C₁₁H₁₄Cl₃N₃O₃S
• Molecular Weight: 374.675
• Mol file: 882739-51-7.mol

Synonyms:[1-Amino-1-phenethylamino-meth-(Z)-ylidene]-sulfamic acid 2,2,2-trichloro-ethyl ester

Chemical Property of [1-Amino-1-phenethylamino-meth-(Z)-ylidene]-sulfamic acid 2,2,2-trichloro-ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [1-Amino-1-phenethylamino-meth-(Z)-ylidene]-sulfamic acid 2,2,2-trichloro-ethyl ester

There total 1 articles about [1-Amino-1-phenethylamino-meth-(Z)-ylidene]-sulfamic acid 2,2,2-trichloro-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

S-methyl-N-(2,2,2-trichloroethoxysulfonyl)isothiourea (882739-47-1) + phenethylamine (64-04-0) → [1-Amino-1-phenethylamino-meth-(Z)-ylidene]-sulfamic acid 2,2,2-trichloro-ethyl ester (882739-51-7)

Guidance literature:

In water; at 100 ℃; for 4h;

DOI:10.1021/ol052920y

Reference yield: 57.0%

[1-Amino-1-phenethylamino-meth-(Z)-ylidene]-sulfamic acid 2,2,2-trichloro-ethyl ester (882739-51-7) → 2-(2,2,2-trichloroethoxysulfonylimino)-4-phenylimidazolidine

Guidance literature:

With [bis(acetoxy)iodo]benzene; magnesium oxide; Rh₂(esp)2; In toluene; at 40 ℃; for 12h;

DOI:10.1021/ol052920y

Reference yield:

[1-Amino-1-phenethylamino-meth-(Z)-ylidene]-sulfamic acid 2,2,2-trichloro-ethyl ester (882739-51-7) → 4-phenyl-4,5-dihydro-1(3)H-imidazol-2-ylamine (89145-85-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 57 percent / PhI(OAc)2; MgO / Rh2(α,α,α',α'-tetramethyl-1,3-benzenedipropionate)2 / toluene / 12 h / 40 °C

2: Zn; acetic acid / Rh2(α,α,α',α'-tetramethyl-1,3-benzenedipropionate)2 / methanol / 16 h / 40 °C

With [bis(acetoxy)iodo]benzene; magnesium oxide; acetic acid; zinc; Rh₂(esp)2; In methanol; toluene;

DOI:10.1021/ol052920y

upstream raw materials:

S-methyl-N-(2,2,2-trichloroethoxysulfonyl)isothiourea

phenethylamine

Downstream raw materials:

4-phenyl-4,5-dihydro-1⁽³⁾H-imidazol-2-ylamine