4-ethynylphenylisocyanate

Base Information

• Chemical Name: 4-ethynylphenylisocyanate
• CAS No.: 814264-50-1
• Molecular Formula: C₉H₅NO
• Molecular Weight: 143.145
• Mol file: 814264-50-1.mol

Synonyms:4-ethynylphenylisocyanate

Chemical Property of 4-ethynylphenylisocyanate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-ethynylphenylisocyanate

There total 2 articles about 4-ethynylphenylisocyanate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

bis(trichloromethyl) carbonate (32315-10-9) + 4-Ethynylaniline (14235-81-5) → 4-ethynylphenylisocyanate (814264-50-1)

Guidance literature:

With triethylamine; In dichloromethane; at 0 ℃; Inert atmosphere;

Reference yield:

4-Ethynylaniline (14235-81-5) + 1,1'-carbonyldiimidazole (530-62-1) → 4-ethynylphenylisocyanate (814264-50-1)

Guidance literature:

In dichloromethane;

Reference yield: 61.0%

4-ethynylphenylisocyanate (814264-50-1) + 1-benzyl-4-[1-hydroxy-2-(trityloxy)ethyl]imidazolidin-2-one → 1-[1-benzyl-2-oxoimidazolidin-4-yl]-2-(trityloxy)ethyl (4-cyanophenyl)carbamate

Guidance literature:

With copper(l) chloride; In dichloromethane; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1055/s-0031-1289684

upstream raw materials:

4-Ethynylaniline

1,1'-carbonyldiimidazole

bis(trichloromethyl) carbonate

Downstream raw materials:

N-4,6-dioxo-5,5-di-(2-propenyl)-1,4,5,6-tetrahydropyrimidin-2-yl-N'-(4-ethynylphenyl)urea

1-(5,5-dibutyl-1,4,5,6-tetrahydro-4,6-dioxopyrimidin-2-yl)-3-(4-ethynylphenyl)urea