C₂₂H₁₉⁽²⁾H₂N₃O₄

Base Information

• Chemical Name: C₂₂H₁₉⁽²⁾H₂N₃O₄
• CAS No.: 77924-78-8
• Molecular Formula: C₂₂H₂₁N₃O₄
• Molecular Weight: 393.411
• Mol file: 77924-78-8.mol

Synonyms:C₂₂H₁₉⁽²⁾H₂N₃O₄

Chemical Property of C₂₂H₁₉⁽²⁾H₂N₃O₄

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of C₂₂H₁₉⁽²⁾H₂N₃O₄

There total 1 articles about C₂₂H₁₉⁽²⁾H₂N₃O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4,9-Dihydropyrano<3,4-b>indol-1(3H)-on (6250-88-0) → C22H19(2)H2N3O4 (77924-78-8)

Guidance literature:

Multi-step reaction with 10 steps

1: 90 percent / LiOH / methanol / 2 h

2: 89 percent / diethyl ether; tetrahydrofuran / 3 h

3: 95 percent / Hydrazine Hydrate, KOH / bis-(2-hydroxy-ethyl) ether / 7 h / 100 - 200 °C

4: 98.5 percent / Imidazole / dimethylformamide / 168 h

5: tert-Butylhypochlorite, Triethylamine / CH₂Cl₂ / 1 h / -78 °C

6: 74 percent / methanol / 120 h

7: 90 percent / ethyl acetate / 4 h / Ambient temperature

8: 91 percent / 18-crown-6 / acetonitrile / 48 h / 60 °C

9: γ-Collidine / benzene / 1 h / 25 °C

10: Triethylamine / 1.) benzene, 90 deg C, 2.) CH₂CL₂, 1h

With 1H-imidazole; 2,4,6-trimethyl-pyridine; potassium hydroxide; lithium hydroxide; 18-crown-6 ether; tert-butylhypochlorite; hydrazine hydrate; triethylamine; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; ethyl acetate; N,N-dimethyl-formamide; acetonitrile; diethylene glycol; benzene;

DOI:10.1021/jo00329a029

upstream raw materials:

4,9-Dihydropyrano<3,4-b>indol-1(3H)-on